S9012

Sulforhodamine B sodium salt

Powder

• Sinónimos: Acid red 52; Acid Rhodamine B
• Fórmula empírica (notación de Hill): C₂₇H₂₉N₂NaO₇S₂
• Número CAS: 3520-42-1
• Peso molecular: 580.65
• UNSPSC Code: 12171500
• NACRES: NA.47
• PubChem Substance ID: 24899824
• EC Number: 222-529-8
• MDL number: MFCD00010180
• Colour Index Number: 45100
• Beilstein/REAXYS Number: 3886008

Propiedades

• Nombre del producto: Sulforhodamine B sodium salt, Technical grade
• Quality Segment: 200
• form: powder
• composition: Dye content, ~75%
• εmax: ≥85000 at 554-560 nm
• application(s): diagnostic assay manufacturing; hematology; histology
• storage temp.: room temp
• SMILES string: [Na+].CCN(CC)c1ccc2c(OC3=CC(\C=CC3=C2c4ccc(cc4S([O-])(=O)=O)S([O-])(=O)=O)=[N+](\CC)CC)c1
• InChI: 1S/C27H30N2O7S2.Na/c1-5-28(6-2)18-9-12-21-24(15-18)36-25-16-19(29(7-3)8-4)10-13-22(25)27(21)23-14-11-20(37(30,31)32)17-26(23)38(33,34)35;/h9-17H,5-8H2,1-4H3,(H-,30,31,32,33,34,35);/q;+1/p-1
• InChI key: SXQCTESRRZBPHJ-UHFFFAOYSA-M

Descripción

General description

Sulforhodamine B (also known as SRB, kiton rhodamine B, lissamine rhodamine B, or sulphorhodamine B) is a bright-pink anionic, aminoxanthene dye carrying two sulfonate substituents.

Application

Sulforhodamine B (SRB) is known for use in SRB assay for the determination of in vitro cytotoxicity through staining and the observation of live cells, proliferation and drug screening.

It has been used in the SRB assay to evaluate the effect of mouthwashes on protein content in primary cultures of human fibroblasts.

It is also suitable as a microscopic tracer for the assessment of blood-brain barrier integrity by post mortem inspection of frozen sections. SRB is useful as a caries detector dye with subsequent inspection of histological material.

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• ¿Qué está pasando?: WGK 2
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable
• EPI (equipos de protección individual): Eyeshields, Gloves, type N95 (US)