SAB6012079

Anti Growth differentiation factor 3 Antibody, clone 23GB5540, Rabbit Monoclonal

clone 23GB5540, recombinant rabbit monoclonal, expressed in HEK293 cells

• Sinónimos: GDF-3, KFS3, MCOP7
• UNSPSC Code: 12352203

Propiedades

• biological source: rabbit (Monoclonal)
• Quality Level: 100
• recombinant: expressed in HEK 293 cells
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: 23GB5540, recombinant monoclonal
• form: buffered aqueous glycerol solution
• mol wt: 41 kDa
• species reactivity: human, rat
• packaging: vial of 1.5 mL
• enhanced validation: recombinant expression; Learn more about Antibody Enhanced Validation
• sustainability: Greener Alternative Product
• concentration: 1.3 mg/ml
• technique(s): western blot: 1:1,000-1:5,000
• isotype: IgG
• Ensembl | human accession no.: ENSG00000184344
• NCBI accession no.: NP_065685.1
• UniProt accession no.: Q9NR23
• greener alternative category: DfS-Developed
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... GDF3(9573)

Descripción

General description

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016]

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Immunogen

A synthesized peptide corresponding to a sequence within amino acids 300-364 of human GDF3 [NP_065685.1].

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.