SML0803

VUF10661

≥98% (HPLC), Chemokine receptor CXCR3 agonist, powder

• Sinónimos: (3S)-N-[(1S)-5-Amino-1-[[(2,2-diphenylethyl)amino]carbonyl]pentyl]-2-(1,4-dioxo-4-phenylbutyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide
• Fórmula empírica (notación de Hill): C₄₀H₄₄N₄O₄
• Número CAS: 914291-63-7
• Peso molecular: 644.80
• UNSPSC Code: 51111800
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• Nombre del producto: VUF10661, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 10 mg/mL, clear
• storage temp.: −20°C

Descripción

Biochem/physiol Actions

VUF10661 is a potent agonist of the chemokine receptor CXCR3.

VUF10661 is a potent agonist of the chemokine receptor CXCR3. VUF10661 induces receptor internalization, recruitment of ?-arrestins and activates Gi proteins with similar potency to endogenous CXCL ligands.

Features and Benefits

This compound is featured on the Chemokine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Información de seguridad

• Pictogramas: GHS06
• Palabra de advertencia: Danger
• Códigos de peligro: H301,H315,H319,H335,H413
• Indicaciones de precaución: P273 - P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Chronic 4 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órganos diana: Respiratory system
• Clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• ¿Qué está pasando?: WGK 3
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable