SML4232

SPC-839

≥98% (HPLC)

• Sinónimos: 1-[[5-methoxy-2-(2-thienyl)-4-quinazolinyl]amino]-3-methyl-1H-pyrrole-2,5-dione, SPC 839, AS602868
• Fórmula empírica (notación de Hill): C₁₈H₁₄N₄O₃S
• Número CAS: 219773-55-4
• Peso molecular: 366.39
• UNSPSC Code: 12352200
• Assay: ≥98% (HPLC)
• Form: powder

Propiedades

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear (warmed)
• storage temp.: 2-8°C

Descripción

Biochem/physiol Actions

SPC-839 is a potent suppressors of T cell activation that covalently targets XPO1 at Cys 528. It potently inhibits inflammation in mice with minimal impact on nuclear export and cell viability. SPC-839 exhibits efficacy in in vivo models of autoimmune disease.

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable