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Merck

CYP2C9

cytochrome P450, family 2, subfamily C, polypeptide 9

Sinonimi:
CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9
Specie:
Human CYP2C9 (1559)
ID UniProtKB:
P11712, P11713, Q16756, Q16872, Q5VX92
ID gene:
  • Human(1559) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008]

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Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
SAB6012093
Anti Cytochrome P450 2C9 Antibody, clone 23GB5885, Rabbit Monoclonal, clone 23GB5885, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reattività con
human
Applicazione
flow cytometry
western blot
HPA015066
Anti-CYP2C9 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
western blot
SAB1305083
MONOCLONAL ANTI-CYP2C9 (N-TERMINAL) antibody produced in mouse, crude ascites, buffered aqueous solution,
Reattività con
human
Applicazione
western blot

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
T8904
Thiabendazole, ≥99%, powder,
Specie
human
T5535
Thiabendazole, BioReagent, suitable for plant cell culture, powder,
Specie
human
M1390
3,3′-Methylene-bis(4-hydroxycoumarin), ,
Specie
human
S0758
Sulfaphenazole, ≥98%,
Specie
human
B5774
Benzbromarone, analytical standard,
Specie
human

Proteins

Numero di prodotto
Descrizione
Specie
MTOXCE2C9
CypExpress™ 2C9 Cytochrome P450 human, ,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
EHU111841
MISSION® esiRNA, targeting human CYP2C9,
Specie
human

Small Molecule - Substrate

Numero di prodotto
Descrizione
Specie
T0891
Tolbutamide, analytical standard,
Specie
human, mouse