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IL1A

interleukin 1, alpha

Synonyms:
IL-1A, IL1, IL1-ALPHA, IL1F1
Species:
UniProtKB ID:
Gene ID:
  • Human(3552) Summary: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq, Jul 2008]
  • Mouse(16175) interleukin 1 alpha
  • Rat(24493) interleukin 1 alpha
  • naked mole-rat(101703933) interleukin 1, alpha
  • domestic guinea pig(100135555) interleukin 1, alpha
  • Domestic Rabbit(100009250) interleukin 1, alpha
  • cow(281250) interleukin 1, alpha
  • dog(403782) interleukin 1, alpha
  • domestic cat(493944) interleukin 1, alpha
  • Goat(100861289) interleukin 1, alpha
  • Horse(100064969) interleukin 1, alpha
  • sheep(443404) interleukin 1, alpha

Custom & Knockdown Gene Products

ELISA

Product Number
Description
Species
Rat IL-1 α ELISA Kit, for serum, plasma and cell culture supernatant,
Species
rat
Mouse IL-1 α ELISA Kit, for serum, plasma and cell culture supernatant,
Species
mouse
Equine IL-1alpha ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
horse
Porcine IL-1 alpha ELISA, for serum, plasma and cell culture supernatants,
Species
Human IL-1 α ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-IL-1α Antibody, clone 3L16 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse
Application
ELISA
affinity binding assay

immunocytochemistry

western blot
Anti-IL-1α Antibody, clone 7E5.14.5, ,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-IL-1α Antibody, clone ALF-161, ,
Species Reactivity
mouse
Application
ELISA
immunoprecipitation (IP)

inhibition assay

radioimmunoassay

western blot
Anti-Interleukin-1α antibody produced in goat, IgG fraction of antiserum, lyophilized powder,
Species Reactivity
human
Application
neutralization
western blot
Monoclonal Anti-Interleukin-1α propeptide antibody produced in mouse, clone 409405, purified immunoglobulin, lyophilized powder,
Species Reactivity
human
Application
western blot

Proteins

Product Number
Description
Species
IL-1ALPHA human, Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC),
Species
human
Interleukin-1α from rat, IL-1α, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Species
rat
Interleukin-1α from mouse, IL-1α, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Species
human
Interleukin-1α human, IL-1α, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human IL1A,
Species
human