CRH
corticotropin releasing hormone
Sinonimi:
CRF
Specie:
Human CRH (1392), Mouse Crh (12918), Rat Crh (81648), chicken CRH (404297), dog CRH (486977), domestic cat CRH (692345), cow CRH (280755), Domestic Rabbit CRH (100301553), sheep CRH (101121525), domestic guinea pig Crh (100719294)
ID UniProtKB:
ID gene:
- Human(1392) Summary: Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition. [provided by RefSeq, Apr 2010]
- Mouse(12918) corticotropin releasing hormone
- Rat(81648) corticotropin releasing hormone
- chicken(404297) corticotropin releasing hormone
- dog(486977) corticotropin releasing hormone
- domestic cat(692345) corticotropin releasing hormone
- cow(280755) corticotropin releasing hormone
- Domestic Rabbit(100301553) corticotropin releasing hormone
- sheep(101121525) corticotropin releasing hormone
- domestic guinea pig(100719294) corticotropin releasing hormone
- naked mole-rat(101717831) corticotropin releasing hormone
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Small Molecule - Agonist
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Specie
Small Molecule - Antagonist
Numero di prodotto
Descrizione
Specie
Antibodies
Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-CRH antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
western blot
Anti-Corticotropin Releasing Factor antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reattività con
bovine, canine, frog, human, mouse, pig, rat, sheep
Applicazione
immunohistochemistry
microarray
radioimmunoassay
microarray
radioimmunoassay
Proteins
Numero di prodotto
Descrizione
Specie
Corticotropin Releasing Factor, Human and Rat, An immunomodulatory neuropeptide that acts to release ACTH from the anterior pituitary and stimulates the sympathetic nervous system and adrenal medulla.,
Specie
human