GNRHR
gonadotropin-releasing hormone receptor
Sinonimi:
GNRHR1, GRHR, HH7, LHRHR, LRHR
Specie:
Human GNRHR (2798), Mouse Gnrhr (14715), Rat Gnrhr (81668), domestic cat GNRHR (101088838), chicken GNRHR (427517), dog GNRHR (403718), Domestic Rabbit GNRHR (100009509), naked mole-rat Gnrhr (101704341), domestic guinea pig Gnrhr (100135532), Horse GNRHR (100033874)
ID UniProtKB:
ID gene:
- Human(2798) Summary: This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. [provided by RefSeq, Jul 2008]
- Mouse(14715) gonadotropin releasing hormone receptor
- Rat(81668) gonadotropin releasing hormone receptor
- domestic cat(101088838) gonadotropin-releasing hormone receptor
- chicken(427517) gonadotropin-releasing hormone receptor
- dog(403718) gonadotropin-releasing hormone receptor
- Domestic Rabbit(100009509) gonadotropin-releasing hormone receptor
- naked mole-rat(101704341) gonadotropin-releasing hormone receptor
- domestic guinea pig(100135532) gonadotropin releasing hormone receptor
- Horse(100033874) gonadotropin-releasing hormone receptor
- cow(281798) gonadotropin-releasing hormone receptor
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Small Molecule - Agonist
Numero di prodotto
Descrizione
Specie
Goserelin for NMR identification, European Pharmacopoeia (EP) Reference Standard,
Specie
human
Small Molecule - Antagonist
Antibodies
Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-GnRH-R Antibody, clone F1G4, clone FIG4, from mouse,
Reattività con
human
Applicazione
ELISA
dot blot
flow cytometry
immunohistochemistry
western blot
dot blot
flow cytometry
immunohistochemistry
western blot
Anti-GNRHR antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse
Applicazione
ELISA
immunofluorescence
immunofluorescence
Anti-GNRHR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunohistochemistry
esiRNA
Numero di prodotto
Descrizione
Specie