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Adenosine 5′-triphosphate dipotassium salt hydrate

Name: Adenosine 5&#8242;-triphosphate dipotassium salt hydrate
Brand: SIGMA
Price: 101 USD
Availability: InStock

≥92% (HPLC), microbial, powder

Synonym(s):

ATP, 5′-ATP-K₂

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Pack Size	SKU	Availability	Price
1 g		Available to ship TODAYfromMILWAUKEE	$101.00
5 g		Available to ship TODAYfromMILWAUKEE	$369.00

About This Item

Empirical Formula (Hill Notation):

C₁₀H₁₄K₂N₅O₁₃P₃ · xH₂O

CAS Number:

42373-41-1

Molecular Weight:

583.36 (anhydrous basis)

MDL number:

MFCD00084672

UNSPSC Code:

41106305

eCl@ss:

32160414

PubChem Substance ID:

24891383

NACRES:

NA.51

Assay:

≥92% (HPLC)

Biological source:

microbial

Form:

powder

Solubility:

H₂O: 50 mg/mL

Storage temp.:

−20°C

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Properties

Product Name

Adenosine 5′-triphosphate dipotassium salt hydrate, from microbial, ≥92% (HPLC)

biological source

microbial

Quality Level

200

assay

≥92% (HPLC)

form

powder

solubility

H₂O: 50 mg/mL

storage temp.

−20°C

SMILES string

[K+].[K+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O

InChI

1S/C10H16N5O13P3.2K/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1

InChI key

YFPSRAQDZYNYPX-IDIVVRGQSA-L

Description

General description

Adenosine 5′-triphosphate (ATP) is synthesized in mitochondria by oxidative phosphorylation.

Application

Adenosine 5′-triphosphate dipotassium salt hydrate has been used:

in in vitro transcription reaction as nucleotide source and in 2x RNA binding buffer
as a component of energy solution for calibrating crude cell extract
to test its dependency with PK11195 in mediating autophagy

Biochem/physiol Actions

P₂ purinergic agonist; increases activity of Ca²⁺-activated K⁺ channels; substrate for ATP-dependent enzyme systems.

Adenosine 5′-triphosphate (ATP) is a central component of energy storage and metabolism in vivo. ATP is used in many cellular processes, respiration, biosynthetic reactions, motility, and cell division. ATP is a substrate of many kinases involved in cell signaling and of adenylate cyclase(s) that produce the second messenger cAMP. ATP provides the metabolic energy to drive metabolic pumps. Metabolic disorders lead to ATP deficiency. Use of xanthine oxidoreductase inhibitors and inosine improves intracellular ATP levels.

Disclaimer

For maximum stability, store as frozen solution at pH 3.5 to 6.8.

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1 of 1

This Item	A1852	A2383	A3377
Sigma-Aldrich A8937 Adenosine 5′-triphosphate dipotassium salt hydrate	Sigma-Aldrich A1852 Adenosine 5′-triphosphate (ATP) disodium salt hydrate	Sigma-Aldrich A2383 Adenosine 5′-triphosphate disodium salt hydrate	Sigma-Aldrich A3377 Adenosine 5′-triphosphate disodium salt hydrate
biological source microbial	biological source microbial (Corynebacterium sp.)	biological source microbial	biological source microbial
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
form powder	form powder	form powder	form crystalline
assay ≥92% (HPLC)	assay ≥99% (HPLC)	assay ≥99%	assay ≥97% (HPLC)
solubility H₂O: 50 mg/mL	solubility water: 50 mg/mL, clear, colorless	solubility H₂O: 50 mg/mL	solubility H₂O: 50 mg/mL
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C

ppe

dust mask type N95 (US), Eyeshields, Gloves

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number

0000557440

0000494549

0000421363

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Global Trade Item Number

SKU	GTIN
A8937-5G	04061833400951
A8937-1G	04061833400944

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