14-909-M

MELK Protein, active, 0 0

Active, recombinant human MELK (amino acids 1 -340), containing an N-terminal GST tag, for use in Kinase Assays.

• Synonym(e): HPK38, PK38, pEg3 kinase
• UNSPSC Code: 12352202
• NACRES: NA.32
• eCl@ss: 32160405
• Biological source: human
• Recombinant: expressed in baculovirus infected insect cells
• Mol wt: M_w 66 kDa

Eigenschaften

• biological source: human
• Quality Segment: 300
• recombinant: expressed in baculovirus infected insect cells
• mol wt: M_w 66 kDa
• manufacturer/tradename: Upstate^®
• technique(s): activity assay: suitable (kinase)
• UniProt accession no.: Q14680
• Gene Information: human ... MELK(9833)

Beschreibung

General description

Maternal embryonic leucine zipper kinase (MELK) is a conserved serine/threonine kinase involved in a variety of cellular functions, including proliferation, differentiation and apoptosis. Its levels are elevated in a number of tumour types and it may be a prognosis marker for some cancers.

Product Source: Recombinant protein of the human MELK gene expressed by baculovirus in insect cells

Recombinant human MELK (amino acids 1 - 340), containing an N-terminal GST tag

Application

Research Category
Signaling

Biochem/physiol Actions

Target Sub-Family: CAMK

Packaging

Also available in 250μg size - call for pricing and availability and reference catalog number 14-909M when ordering the 250μg size

Physical form

Purified using glutathione-agarose

Preparation Note

6 months at -70°C

Analysis Note

Routinely evaluated by phosphorylation of KKLNRTLSFAEPG

Other Notes

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• Gefahrencodes: H317
• Sicherheitshinweise: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Hazard Classifications: Skin Sens. 1
• Lagerklasse: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable