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3570

Glycin

Synonym(e):

Glycin, Aminoessigsäure, Aminoethansäure, Glycokoll

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Über diesen Artikel

Lineare Formel:
NH2CH2COOH
CAS-Nummer:
Molekulargewicht:
75.07
NACRES:
NA.54
UNSPSC Code:
12352209
Beilstein/REAXYS Number:
635782
MDL number:
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description

RTECS - MB7600000
Merck USA index - 14, 4491

Quality Segment

assay

>99% (by assay)

form

crystalline solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

impurities

≤100 CFU/g Total microorganism, ≤6.0 EU/g Endotoxin

color

white

pKa (25 °C)

(1) 2.35, (2) 9.60, 2.35

mp

240 °C (dec.) (lit.)

solubility

water: 250 mg/mL

cation traces

Fe: ≤10 ppm, heavy metals (as Pb): ≤5 ppm

shipped in

ambient

storage temp.

15-25°C

SMILES string

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

General description

Eine essenzielle, optisch inaktive, nicht chirale Aminosäure. Die kleinste der 20 natürlichen Aminosäuren. Wirkt als hemmender Neurotransmitter, inbesondere im Hirnstamm und im Rückenmark. Blockiert nachweislich die NMDA-stimulierte Dopaminfreisetzung in fötalen mesenzephalen Zellkulturen. Darüber hinaus steigert es Berichten zufolge das NMDA-Rezeptor-vermittelte synaptische Potenzial in kortikalen Neuronen.
Eine unpolare, ungeladene Aminosäure.

Biochem/physiol Actions

Hemmender Neurotransmitter im Rückenmark; allosterischer Regulator von NMDA-Rezeptoren.

Other Notes

Shapiro, S. 1997. Neurosurgery 40, 168.
Mount, H., et al. 1991. Mol. Pharmacol.39, 205.
Thompson, A.M., et al. 1989. Nature338, 422.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxizität: Standard-Handhabung (A)

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Dieser Artikel
7652415527G0450000
Glycin

Millipore

3570

Glycin

Glycin certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Supelco

76524

Glycin

Glycin European Pharmacopoeia (EP) Reference Standard

G0450000

Glycin

description

-

description

certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

description

meets analytical specification of Ph. Eur., BP, USP, 99-101% (based on anhydrous substance)

description

European Pharmacopoeia (EP) Reference Standard

form

crystalline solid

form

-

form

crystalline powder

form

-

assay

>99% (by assay)

assay

-

assay

99-101% (based on anhydrous substance)

assay

-

storage temp.

15-25°C

storage temp.

15-25°C

storage temp.

-

storage temp.

2-8°C

impurities

≤6.0 EU/g Endotoxin, ≤100 CFU/g Total microorganism

impurities

-

impurities

≤1.0% ninhydrin-positive substances, organic volatile impurities, complies (GC), hydrolyzable substances, complies, residual solvents, complies, ≤0.001% heavy metals (as Pb)

impurities

-

mp

240 °C (dec.) (lit.)

mp

240 °C (dec.) (lit.)

mp

240 °C (dec.) (lit.)

mp

240 °C (dec.) (lit.)

cation traces

heavy metals (as Pb): ≤5 ppm, Fe: ≤10 ppm

cation traces

-

cation traces

-

cation traces

-


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Lagerklasse

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

No data available

flash_point_c

No data available



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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

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