MAP2MAG-76K

MILLIPLEX^® Mouse Acute Phase Panel 2

Configurable Mouse Acute Phase 6-Plex Panel 2

• Synonym(e): acute phase proteins, immune response proteins, immunoassay targets, inflammation-related analytes, inflammatory biomarkers, mouse cytokine markers, mouse inflammation markers, plasma proteins, preclinical inflammation indicators, serum biomarkers
• UNSPSC Code: 12161503
• NACRES: NA.84
• eCl@ss: 32161000

Eigenschaften

• Produktname: MILLIPLEX^® Mouse Acute Phase Panel 2, Configurable Mouse Acute Phase 6-Plex Panel 2
• Quality Segment: 200
• product line: Milliplex^®
• species reactivity: mouse
• packaging: pkg of 1 ea
• technique(s): multiplexing: suitable
• input: plasma; tissue/cellular extract(s); cell culture supernatant(s); serum
• assay range: accuracy: 99.2-128.2%, sensitivity: 0.001-7.495 ng/mL, standard curve range: 0.001-0.5 ng/mL; (AGP), standard curve range: 0.005-4.0 ng/mL; (Adipsin), standard curve range: 0.014-10 ng/mL; (CRP), standard curve range: 0.549-400 ng/mL; (Haptoglobin), standard curve range: 13.717-10,000 ng/mL; (SAP), standard curve range: 6.858-5000 ng/mL; (A2M), inter-assay cv: <15%; intra-assay cv: <10%
• detection method: fluorometric (Luminex^® xMAP^® technology)
• shipped in: wet ice
• storage temp.: 2-8°C

Beschreibung

General description

Metabolic hormones such as insulin, leptin, ghrelin, adiponectin, and resistin are central to regulating energy balance, appetite, and glucose metabolism. Insulin promotes cellular glucose uptake, leptin signals satiety, and ghrelin stimulates hunger, while adiponectin enhances insulin sensitivity and resistin contributes to inflammation and insulin resistance. Their coordinated activity reflects the body’s metabolic state and is crucial for understanding disorders like obesity and diabetes.

Application

MILLIPLEX^® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 6 analytes in mouse serum, plasma, or cell culture supernatants.

Analytes included: α-1-Acid Glycoprotein (AGP), α-2-Macroglobulin, Adipsin (Factor D), C-Reactive Protein (CRP), Haptoglobin, Serum Amyloid P (SAP).

Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

Features:

• Measures key metabolic hormones involved in energy regulation and glucose metabolism
• Includes analytes such as insulin, leptin, ghrelin, adiponectin, and resistin
• Enables simultaneous profiling for a comprehensive metabolic overview
• Applicable to various biological samples like serum, plasma, and tissue extracts - Suitable for both research and clinical applications

Benefits:

• Detects early signs of metabolic dysfunction such as insulin resistance and obesity
• Supports evaluation of therapeutic interventions targeting metabolic pathways
• Enhances understanding of hormonal interactions in metabolic disorders
• Provides valuable data for tracking disease progression and recovery
• Facilitates personalized approaches to managing metabolic health

Legal Information

Luminex is a registered trademark of Luminex Corporation

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.




Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Sicherheitshinweise

• Piktogramme: GHS06,GHS08,GHS05,GHS09
• Signalwort: Danger
• Gefahrencodes: H302 + H332,H311,H317,H318,H373,H411
• Sicherheitshinweise: P273 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P314
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
• Zielorgane: Respiratory Tract
• Lagerklasse: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Was ist los?: WGK 3