SYNPLE-B021

Reagent-cartridge Silyl deprotection

Synple

• Synonym(e): Synple 2
• UNSPSC Code: 12352401
• NACRES: NA.22
• MDL number: MFCD32903606
• eCl@ss: 32039090

Eigenschaften

• reaction suitability: reaction type: Alcohol Protection
• manufacturer/tradename: SynpleChem
• SMILES string: [s]1cnc(c1c2ccc(cc2)CNC(=O)[C@H]3N(C[C@@H](C3)O)C(=O)[C@@H](NC(=O)CCOCCC(=O)O)C(C)(C)C)C
• InChI key: HVPZHRHEHKZOOJ-TYBLODHISA-N

Beschreibung

General description

Reagent-cartridge Silyl deprotection is a reagent cartridge for the Synple 2 Automated Synthesizer that enables the silyl deprotection of primary and secondary alcohols. The cartridge contains all necessary reagents to perform the deprotection of TBS, TES, and TIPS protected alcohols.

Scale: up to 0.5 mmol

Compatible protecting groups: TBS, TES, TIPS (primary or secondary alcohols)

Cartridge contents:

• pTsOH•H2O (for deprotection)
• Silica supported triethylamine (for purification)

Learn more about the Synple automated synthesis platform.

Features and Benefits of Synple Platform

• Time savings – pre-installed protocols have been highly optimized, which obviates the need for the user’s own reaction development and optimization
• Easy to use – protocols are loaded by simply scanning the cartridge; does not requires any programming knowledge
• Safety – all chemicals are contained in the system, minimizing the user’s exposure
• Set-up reaction in less than 5 minutes
• Small footprint
• Plug & Play system – simple installation
• Reaction temperatures from 25 °C – 80 °C
• Cartridges available for many different reactions
• Prefilled with all required reagents
• RFID chip containing optimized reaction protocol

Other Notes

References
An integrated console for capsule-based, automated organic synthesis

Legal Information

Product of Synple Chem AG

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• Gefahrencodes: H315,H319
• Sicherheitshinweise: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Lagerklasse: 8B - Non-combustible corrosive hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable