7-Amino-4-methyl-3-cumarinessigsäure-N-succinimidylester

Name: 7-Amino-4-methyl-3-cumarinessigsäure-<I>N</I>-succinimidylester
Brand: SIGMA

BioReagent, suitable for fluorescence, ≥90% (HPLC)

Synonym(e):

7-(Dimethylamino)-cumarin-4-essigsäure-NHS, 7-Amino-4-methyl-3-cumarinessigsäure-N-succinimidylester, 7-Amino-4-methyl-3-cumarinylacetyl, N-Succinimidyl-7-amino-4-methyl-3-cumarinylacetat, AMCA-NHS, Succinimidyl-7-amino-4-methylcumarin-3-acetat

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Über diesen Artikel

Empirische Formel (Hill-System):

C₁₆H₁₄N₂O₆

CAS-Nummer:

113721-87-2

Molekulargewicht:

330.29

NACRES:

NA.32

PubChem Substance ID:

329748586

UNSPSC Code:

12352108

MDL number:

MFCD00036170

Beilstein/REAXYS Number:

9007679

Technischer Dienst

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Eigenschaften

product line

BioReagent

Quality Segment

100

assay

≥90% (HPLC)

solubility

DMF: soluble, DMSO: soluble

fluorescence

λ_ex 354 nm; λ_em 440 nm in methanol

suitability

suitable for fluorescence

storage temp.

−20°C

SMILES string

CC1=C(CC(=O)ON2C(=O)CCC2=O)C(=O)Oc3cc(N)ccc13

InChI

1S/C16H14N2O6/c1-8-10-3-2-9(17)6-12(10)23-16(22)11(8)7-15(21)24-18-13(19)4-5-14(18)20/h2-3,6H,4-5,7,17H2,1H3

InChI key

ILKQVTIMOGNSAS-UHFFFAOYSA-N

Beschreibung

Application

AMCA-NHS has been utilized in the development of a donor europium chelate fluorochrome for use in LRET based analyses by first reacting with an amino group and then with DTPA anhydride . Utilized in FRET based studies, acting as the donor dye and can be paired with fluorescein-5-isothiocyanate as the acceptor dye . A blue fluorescent dye reactive towards primary amine groups on proteins, peptides, antibodies, and other biomolecules (at pH 7.0-9.0).