27883

Coumestrol

BioReagent, suitable for fluorescence, ≥97.5% (HPLC)

• Synonym(e): 7,12-Dihydroxy-coumestan
• Empirische Formel (Hill-System): C₁₅H₈O₅
• CAS-Nummer: 479-13-0
• Molekulargewicht: 268.22
• UNSPSC Code: 41116107
• NACRES: NA.77
• PubChem Substance ID: 57648278
• EC Number: 207-525-6
• Beilstein/REAXYS Number: 266702
• MDL number: MFCD00016885

Eigenschaften

• product line: BioReagent
• assay: ≥97.5% (HPLC)
• form: powder
• mp: ≥350 °C (lit.)
• solubility: DMSO: soluble
• fluorescence: λ_ex 377 nm; λ_em 437 nm in 0.1 M Tris pH 8.0
• suitability: suitable for fluorescence
• SMILES string: Oc1ccc-2c(OC(=O)c3c-2oc4cc(O)ccc34)c1
• InChI: 1S/C15H8O5/c16-7-1-3-9-11(5-7)19-14-10-4-2-8(17)6-12(10)20-15(18)13(9)14/h1-6,16-17H
• InChI key: ZZIALNLLNHEQPJ-UHFFFAOYSA-N
• Gene Information: human ... ESR1(2099), ESR2(2100) ; mouse ... Esr1(13982) ; rat ... Ar(24208)

Beschreibung

Biochem/physiol Actions

Coumestrol has anti-estrogenic actions in the brain and pituitary, mediated through estrogen receptor-α.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• Gefahrencodes: H302,H315,H319,H335
• Sicherheitshinweise: P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• PSA (Persönliche Schutzausrüstung): dust mask type N95 (US), Eyeshields, Gloves