61962

Betain

BioUltra, ≥99.0% (NT)

• Synonym(e): (Carboxymethyl)trimethylammonium Inneres Salz, Oxyneurin, Trimethylglycin
• Lineare Formel: (CH₃)₃N⁺CH₂COO^-
• CAS-Nummer: 107-43-7
• Molekulargewicht: 117.15
• Beilstein: 3537113
• EG-Nummer: 203-490-6
• MDL-Nummer: MFCD00012123
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 57651874
• NACRES: NA.25

Eigenschaften

• Produktlinie: BioUltra
• Assay: ≥99.0% (NT)
• Verunreinigungen: insoluble matters, passes filter test
• Löslichkeit: methanol: 1 M at 20 °C, clear, colorless
• Anionenspuren: chloride (Cl^-): ≤200 mg/kg; sulfate (SO₄^2-): ≤200 mg/kg
• Kationenspuren: Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Na: ≤100 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Zn: ≤5 mg/kg
• Absorption: ≤0.05 at 280 nm in methanol at 1 M; ≤0.09 at 260 nm in methanol at 1 M
• SMILES String: C[N+](C)(C)CC([O-])=O
• InChI: 1S/C5H11NO2/c1-6(2,3)4-5(7)8/h4H2,1-3H3
• InChIKey: KWIUHFFTVRNATP-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

Anwendung

Betaine has been used in reverse transcription to increase the thermal stability of proteins and to destabilize the DNA helix.[1]

Biochem./physiol. Wirkung

Als Endprodukt des oxidativen Metabolismus von Cholin ist Betain ein allgemeiner Methyldonator, insbesondere in einem untergeordneten Stoffwechselweg der Methioninbiosynthese. Es wird eingesetzt, um Homozystinurie, ein Defekt im Hauptstoffwechselweg der Methioninbiosynthese, zu behandeln.[2]

Betaine has been shown to increase S-adenosylmethionine (SAM) levels and hence, may have a role in diminishing hepatic steatosis. It is an osmolyte which protects cells against environmental stress.[3][4]

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)