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95144

Retinol

BioXtra, ≥97.5% (HPLC), ~3100 U/mg

Synonym(e):

Axerophthol, Vitamin A, Vitamin A1, Vitamin-A-alkohol, all-trans-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol

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Größe/SKUVerfügbarkeitPreis
250 mg
Warenkorb auf Verfügbarkeit prüfen
€ 159,00
1 g
Warenkorb auf Verfügbarkeit prüfen
€ 482,00

Über diesen Artikel

Empirische Formel (Hill-System):
C20H30O
CAS-Nummer:
Molekulargewicht:
286.45
NACRES:
NA.28
PubChem Substance ID:
eCl@ss:
34058018
UNSPSC Code:
12352205
EC Number:
200-683-7
MDL number:
Beilstein/REAXYS Number:
403040

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biological source

synthetic

Quality Segment

product line

BioXtra

assay

≥97.5% (HPLC)

form

(Powder or Powder with Lumps)

specific activity

~3100 U/mg

shelf life

limited shelf life

color

faint yellow to very dark yellow

mp

56-61 °C, 61-63 °C (lit.)

shipped in

dry ice

storage temp.

−20°C

SMILES string

CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/CO)=C(C)CCC1

InChI

1S/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6+,12-11+,16-8+,17-13+

InChI key

FPIPGXGPPPQFEQ-OVSJKPMPSA-N

General description

Retinol or vitamin A alcohol is the main circulating form of vitamin A.

Application

Retinol has been used:
  • as a standard in peak identification and quantification in reverse phase HPLC
  • as a standard to estimate the concentration of vitamin A
  • to study the inhibitory effect of retinol on murine norovirus (MNV) replication in murine RAW 264.7 cells
  • as a component in the reaction mixture for the lecithin:retinol acyltransferase (LRAT) assay

Biochem/physiol Actions

Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain.
Retinol is biological active in a wide range of processes.
It is not biologically active and works as a precursor of active retinoids. Retinol is converted to retinaldehyde and subsequently to retinoic acid.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

1 U entspricht 1 Internationalen Einheit gemäss Ph Eur II, 217 (1983)

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Dieser Artikel
R763217772R7882
description

BioXtra, ≥97.5% (HPLC), ~3100 U/mg

description

synthetic, ≥95% (HPLC), (Powder or Powder with Lumps)

description

≥95.0% (HPLC), ~2700 U/mg

description

solid or viscous liquid, BioReagent, synthetic, suitable for cell culture

biological source

synthetic

biological source

synthetic

biological source

synthetic

biological source

synthetic

assay

≥97.5% (HPLC)

assay

≥95% (HPLC)

assay

≥95.0% (HPLC)

assay

≥90% (HPLC)

form

(Powder or Powder with Lumps)

form

(Powder or Powder with Lumps)

form

(Powder or Crystal with Lumps)

form

solid or viscous liquid

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

-

mp

61-63 °C (lit.), 56-61 °C

mp

61-63 °C (lit.)

mp

61-63 °C (lit.)

mp

57-58 °C


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Piktogramme

Health hazardExclamation mark

Signalwort

Danger

Hazard Classifications

Aquatic Chronic 4 - Eye Irrit. 2 - Repr. 1B - Skin Sens. 1

Lagerklasse

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Was ist los?

WGK 1

PSA (Persönliche Schutzausrüstung)

dust mask type N95 (US), Eyeshields, Gloves



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Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. Bonjour, je souhaiterais acheter du Retinol (CAS : 68-26-8) afin de réaliser une courbe de calibration pour une méthode d'analyse LC-MS/MS. Il me faudrait donc le plus pur possible. Je souhaiterais savoir ce que signifie 3000 U/mg ?

    1 answer
    1. One unit (the USP unit is the same as the International Unit) of vitamin A is equal to 0.3 micrograms of the pure all-trans isomer of retinol, which is equivalent to 0.344 micrograms of all-trans retinyl acetate. This product is ≥97.5% pure by HPLC. More information and references can be found in the data sheet: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/740/736/95144dat.pdf

      Helpful?

  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

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