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A2093

Aspirin

meets USP testing specifications

Synonym(e):

Acetylsalicylsäure, 2-Acetoxybenzoesäure, ASA, Aspirin

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Größe/SKUVerfügbarkeitPreis
100 g
Warenkorb auf Verfügbarkeit prüfen
€ 41,40
500 g
Warenkorb auf Verfügbarkeit prüfen
€ 127,00

Über diesen Artikel

Lineare Formel:
2-(CH3CO2)C6H4CO2H
CAS-Nummer:
Molekulargewicht:
180.16
UNSPSC Code:
12352106
NACRES:
NA.21
PubChem Substance ID:
EC Number:
200-064-1
Beilstein/REAXYS Number:
779271
MDL number:

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Quality Segment

agency

USP/NF, meets USP testing specifications

form

powder or crystals

mp

134-136 °C (lit.)

application(s)

pharmaceutical (small molecule)

SMILES string

CC(=O)Oc1ccccc1C(O)=O

InChI

1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)

InChI key

BSYNRYMUTXBXSQ-UHFFFAOYSA-N

Gene Information

General description

Aspirin (acetylsalicylic acid) is a nonsteroidal anti-inflammatory drug. It occurs as white crystalline powder and is derived from salicylic acid.

Application

Aspirin has been used:
  • as a stabilizer for blood during 13,14-dihydro-15-keto-prostaglandin F2α (PGFM) measurement
  • to evaluate cell viability of BV-2 microglial cell line
  • in morphogenesis assay

Biochem/physiol Actions

Verhindert durch Hemmung der Cyclooxygenase (Prostaglandin H Synthase) die Produktion von Prostaglandinen mit höher Selektivität für COX-1. Für den antithrombotischen Effekt ist die Hemmung von COX-1 in Thrombozyten verantwortlich, welches die Produktion von Thromboxan und die Blutplättchenaggregation hemmt. Chemopräventive Wirkung gegenüber kolorektalen und anderen soliden Tumoren.
Aspirin is an analgesic and antipyretic agent used in the treatment of fever and pain as in arthritis. It is also associated with cardiovascular diseases.

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Dieser Artikel
BP617Y0001460A0200000
Aspirin British Pharmacopoeia (BP) Reference Standard

BP617

Aspirin

description

meets USP testing specifications

description

British Pharmacopoeia (BP) Reference Standard

description

European Pharmacopoeia (EP) Reference Standard

description

European Pharmacopoeia (EP) Reference Standard

Gene Information

human ... ITGA2B(3674), PTGS1(5742), PTGS2(5743)

Gene Information

human ... PTGS1(5742), PTGS2(5743)

Gene Information

human ... PTGS1(5742), PTGS2(5743)

Gene Information

human ... PTGS1(5742), PTGS2(5743)

Quality Level

200

Quality Level

-

Quality Level

-

Quality Level

-

form

powder or crystals

form

crystalline

form

-

form

-

mp

134-136 °C (lit.)

mp

134-136 °C (lit.)

mp

134-136 °C (lit.)

mp

134-136 °C (lit.)

agency

USP/NF, meets USP testing specifications

agency

-

agency

-

agency

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical
pharmaceutical small molecule

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)


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Piktogramme

Exclamation mark

Signalwort

Warning

Lagerklasse

11 - Combustible Solids

Flammpunkt (°F)

482.0 °F

Flammpunkt (°C)

250 °C

PSA (Persönliche Schutzausrüstung)

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Gefahrencodes

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3



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Analysenzertifikate (COA)

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Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. How to dissolve Aspirin and minimize concentration for storage?

    1 answer
    1. This compound is soluble in ethanol at 50 mg/mL, in water at 3 mg/mL, and in 37 °C water at 10 mg/mL. Acetylsalicylic acid is not stable in aqueous solutions and will readily hydrolyze to salicylic acid. Minimal concentration and solution stability in ethanol have not been established.

      Helpful?

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