If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
Fortfahren mit
A3611
Arachidonsäure
from non-animal source, ≥98.5% (GC)
Synonym(e):
cis,cis,cis,cis-5,8,11,14-Eicosatetraensäure, Immunocytophyt
Größe auswählen
| Größe/SKU | Verfügbarkeit | Preis |
|---|---|---|
10 mg | Warenkorb auf Verfügbarkeit prüfen | € 100,00 |
100 mg | Warenkorb auf Verfügbarkeit prüfen | € 187,00 |
1 g | Warenkorb auf Verfügbarkeit prüfen | € 1.220,00 |
Über diesen Artikel
biological source
non-animal source
Quality Segment
assay
≥98.5% (GC)
form
liquid
refractive index
n20/D 1.4872 (lit.)
bp
169-171 °C/0.15 mmHg (lit.)
mp
−49 °C (lit.)
density
0.922 g/mL at 25 °C (lit.)
functional group
carboxylic acid
lipid type
omega FAs
shipped in
dry ice
storage temp.
−20°C
SMILES string
OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O
InChI
1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15-
InChI key
YZXBAPSDXZZRGB-DOFZRALJSA-N
Application
<li><strong>Molecular Mechanisms Associated with the Inhibitory Role of Long Chain n-3 PUFA in Colorectal Cancer:</strong> In dieser Studie werden die Auswirkungen langkettiger mehrfach ungesättigter Fettsäuren wie Arachidonsäure auf die Mechanismen von Darmkrebs untersucht. Die Forschung konzentriert sich auf die entzündungshemmende und krebshemmende Rolle durch die Modulation des Lipidstoffwechsels und der Signaltransduktionskanäle (Jayathilake et al., 2024).</li>
<li><strong>Zhilining Formula alleviates DSS-induced colitis through suppressing inflammation and gut barrier dysfunction via the AHR/NF-Bp65 axis:</strong> In diesem Artikel wird die Rolle der Arachidonsäure bei der Unterdrückung von Entzündungen und der Wiederherstellung der Barrierefunktion des Darms vorgestellt, die für das Verständnis von Entzündungskrankheiten und die Entwicklung therapeutischer Strategien von entscheidender Bedeutung ist (Zhou et al., 2024).</li>
<li><strong>5,6-diHETE lactone (EPA-L) mediates hypertensive microvascular dilation by activating the endothelial GPR-PLC-IP(3) signaling pathway:</strong> Untersucht die kardiovaskulären Auswirkungen von Arachidonsäure-Metaboliten, insbesondere ihre Rolle bei mikrovaskulären Reaktionen, die sich auf die Behandlungsstrategien bei Hypertonie auswirken könnten (Asulin et al., 2024).</li>
</ul>
Biochem/physiol Actions
Packaging
1 of 1
Dieser Artikel | |||
|---|---|---|---|
| description from non-animal source, ≥98.5% (GC) | description >95.0% (GC) | description analytical standard | description Precursor for prostaglandins, prostacyclin, and thromboxane. |
| biological source non-animal source | biological source fungus | biological source synthetic | biological source - |
| functional group carboxylic acid | functional group carboxylic acid | functional group carboxylic acid | functional group - |
| assay ≥98.5% (GC) | assay >95.0% (GC) | assay ≥97.0% (GC) | assay ≥99% (TLC and GC) |
| storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. −70°C |
| form liquid | form liquid | form liquid | form oil |
| shipped in dry ice | shipped in dry ice | shipped in - | shipped in dry ice |
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Signalwort
Warning
Gefahrencodes
Sicherheitshinweise
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Lagerklasse
10 - Combustible liquids
Was ist los?
WGK 3
Flammpunkt (°F)
235.4 °F - closed cup
Flammpunkt (°C)
113 °C - closed cup
Hier finden Sie alle aktuellen Versionen:
Besitzen Sie dieses Produkt bereits?
In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.
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How can I determine the shelf life / expiration / retest date of this product?
1 answer-
Helpful?
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
Helpful?
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What is the solubility of item A3611, Arachidonic acid?
1 answer-
This product is soluble in DMSO (100 mg/ml), DMF (100 mg/ml), 100% ethanol (50 mg/ml), methanol (50 mg/ml), chloroform (50 mg/ml), dichloromethane, hexane, acetonitrile, and ether.
Helpful?
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what is the volume in the 10mg ampule for A3611- arachidonic acid?
1 answer-
Based on the density of 0.922 g/mL, the volume of the 10 mg package is approximately 0.011mL.
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What is the volume in microL of arachidonic acid (A3611-100 mg) in vial? Please specify the purity (PCode 1003455023).
1 answer-
There is 108 uL in the 100mG pack size. The exact purity will be listed on the Certificate of Analysis. Please see the sample Certificate of Analysis: https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/A3611-1G-PWSLCQ3577.pdf
Helpful?
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May I know the Molarity (M) of the Arachidonic Acid A3611? It was not stated in the SDS.
1 answer-
The concentration for this product will be lot specific as purity changes with each batch. The concentration of this material can be calculated by the following equation: density x 1000 x purity percent divided by the molecular weight. For example, lot SLCQ3577 on the sample certificate of analysis will have a concentration of about 3.01 M
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Hi, I'm used to ordering AA with this same catalogue nr at 10mg in powder form. Now only 100mg in liquid form is available. In which solvent is this?
1 answer-
This is pure arachadonic acid - it is not in any solvent. Its melting point is at -49 deg C. At temperatures above, it will be in its liquid physical state. You can determine the amount by using the density for a calculation. 0.922 g/mL at 25 °C (lit.)
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