A7611

Azelastin -hydrochlorid

≥98% (HPLC)

• Synonym(e): 4-[(4-Chlorphenyl)-methyl]-2-(1-methylazepan-4-yl)-phthalazin-1-on -hydrochlorid, Astelin, Optivar
• Empirische Formel (Hill-System): C₂₂H₂₄ClN₃O · HCl
• CAS-Nummer: 79307-93-0
• Molekulargewicht: 418.36
• NACRES: NA.77
• PubChem Substance ID: 329770938
• UNSPSC Code: 12352200
• MDL number: MFCD00242783
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to off-white
• solubility: DMSO: >10 mg/mL
• originator: Wallace
• storage temp.: −20°C
• SMILES string: Cl.CN1CCCC(CC1)N2N=C(Cc3ccc(Cl)cc3)c4ccccc4C2=O
• InChI: 1S/C22H24ClN3O.ClH/c1-25-13-4-5-18(12-14-25)26-22(27)20-7-3-2-6-19(20)21(24-26)15-16-8-10-17(23)11-9-16;/h2-3,6-11,18H,4-5,12-15H2,1H3;1H
• InChI key: YEJAJYAHJQIWNU-UHFFFAOYSA-N
• Gene Information: human ... HRH1(3269)

Beschreibung

Application

Azelastine hydrochloride is a H1 histamine receptor antagonist and NF-kB activator. Azelastine hydrochloride has been used in a study to investigate the potential of polymeric microspheres for treatment of allergic conjunctivitis.

Biochem/physiol Actions

H1 Histamin-Rezeptor-Antagonist, NF-kB-Aktivator.

Features and Benefits

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Wallace. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• Gefahrencodes: H302
• Sicherheitshinweise: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Lagerklasse: 11 - Combustible Solids
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable