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A9062

Adenosin-5′-Triphosphat Bis-(Tris)-salz Hydrat

Name: Adenosin-5&#8242;-Triphosphat Bis-(Tris)-salz Hydrat
Brand: SIGMA

≥95%, Fermentation, powder

Synonym(e):

5′-ATP-Bis(TRIS)

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Über diesen Artikel

Empirische Formel (Hill-System):

C₁₀H₁₆N₅O₁₃P₃ · 2C₄H₁₁NO₃ · xH₂O

CAS-Nummer:

102047-34-7

Molekulargewicht:

749.45 (anhydrous basis)

MDL number:

MFCD32695621

UNSPSC Code:

41106305

eCl@ss:

32160414

PubChem Substance ID:

24891222

NACRES:

NA.51

Assay:

≥95%

Biological source:

(Fermentation)

Form:

powder

Solubility:

H₂O: 50 mg/mL

Storage temp.:

−20°C

Technischer Dienst

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Unterstützung erhalten

Eigenschaften

Produktname

Adenosin-5′-Triphosphat Bis-(Tris)-salz Hydrat, ≥95%

biological source

(Fermentation)

Quality Segment

200

assay

≥95%

form

powder

solubility

H₂O: 50 mg/mL

cation traces

Na: ≤0.1%

shipped in

dry ice

storage temp.

−20°C

SMILES string

O.NC(CO)(CO)CO.NC(CO)(CO)CO.Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O

InChI

1S/C10H16N5O13P3.2C4H11NO3.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;2*5-4(1-6,2-7)3-8;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);2*6-8H,1-3,5H2;1H2/t4-,6-,7-,10-;;;/m1.../s1

InChI key

ZMNHJZFDZFGOFE-MSQVLRTGSA-N

Beschreibung

Application

Adenosine 5′-triphosphate di(tris) salt hydrate has been used:

to treat cells for Ca²⁺ influx measurements in stromal interaction molecule 1 knockout (STIM1−/−) mice and in vitro chemotaxis assay for microglial migration
supplemented in buffer C for mitochondrial respiratory control assay and complex V activity assay
in the inhibition of silver nano particles (AgNPs) on Na⁺/K⁺-ATPase activity

Biochem/physiol Actions

P₂ purinergener Antagonist; erhöht die Aktivität von Ca²⁺-aktivierten K⁺ Kanälen; Substrat für ATP-abhängigen Enzymsysteme.

Adenosine 5′-triphosphate di(tris) salt dehydrate is useful in applications that require the absence of metals.
Adenosine 5′-triphosphate (ATP) is a central component of energy storage and metabolism in vivo. ATP is use in many cellular processes, respiration, biosynthetic reactions, motility, and cell division. ATP is a substrate of many kinases involved in cell signaling and of adenylate cyclase(s) that produce the second messenger cAMP. ATP provides the metabolic energy to drive metabolic pumps. ATP serves as a coenzyme in a wide array of enzymatic reactions.