A9075

(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyric acid hydrochloride

• Synonym(e): (2S,3R)-AHPA
• Empirische Formel (Hill-System): C₁₀H₁₃NO₃ · HCl
• CAS-Nummer: 128223-55-2
• Molekulargewicht: 231.68
• UNSPSC Code: 12352200
• PubChem Substance ID: 24891224
• MDL number: MFCD00274394

Eigenschaften

• form: solid
• storage temp.: −20°C
• SMILES string: Cl.N[C@H](Cc1ccccc1)[C@H](O)C(O)=O
• InChI: 1S/C10H13NO3.ClH/c11-8(9(12)10(13)14)6-7-4-2-1-3-5-7;/h1-5,8-9,12H,6,11H2,(H,13,14);1H/t8-,9+;/m1./s1
• InChI key: OPVMPYQFOLATCK-RJUBDTSPSA-N

Beschreibung

Biochem/physiol Actions

(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyric acid (AHPA) derivatives are used as inhibitors of enkephalinase(s) to augment met5-enkephalin-induced anti-nociception. The derivative (2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl-L-valine (AHPA-Val) is used as a bestatin analogue.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• Gefahrencodes: H315,H319,H335
• Sicherheitshinweise: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): dust mask type N95 (US), Eyeshields, Gloves