B5311

Biperiden -hydrochlorid

≥98% (HPLC), powder

• Synonym(e): 1-(5-Bicyclo[2.2.1]hept-2-enyl)-1-phenyl-3-(1-piperidinyl)propan-1-ol hydrochloride, Akineton, Akinophyl
• Empirische Formel (Hill-System): C₂₁H₃₀ClNO
• CAS-Nummer: 1235-82-1
• Molekulargewicht: 347.92
• PubChem Substance ID: 329773254
• UNSPSC Code: 12352200
• EC Number: 214-976-2
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: off-white
• solubility: DMSO: >20 mg/mL, H₂O: insoluble
• originator: Abbott
• SMILES string: Cl[H].OC(CCN1CCCCC1)(C2CC3CC2C=C3)c4ccccc4
• InChI: 1S/C21H29NO.ClH/c23-21(19-7-3-1-4-8-19,11-14-22-12-5-2-6-13-22)20-16-17-9-10-18(20)15-17;/h1,3-4,7-10,17-18,20,23H,2,5-6,11-16H2;1H
• InChI key: RDNLAULGBSQZMP-UHFFFAOYSA-N
• Gene Information: human ... CHRM1(1128)

Beschreibung

Biochem/physiol Actions

Antiparkinsonian; non-selective muscarinic receptor antagonist.

Biperiden hydrochloride is antiparkinsonian; non-selective muscarinic receptor antagonist. It is used for the adjunctive treatment of all forms of Parkinson′s Disease (postencephalitic, idiopathic, and arteriosclerotic); also commonly used to improve parkinsonian signs and symptoms related to antipsychotic drug therapy. LD₅₀ in rats 750 mg/kg; in dogs 340 mg/kg.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• Gefahrencodes: H302
• Sicherheitshinweise: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): dust mask type N95 (US), Eyeshields, Gloves