The impurities that may be present in this product have not been identified. These impurites may include water and salts reminaining following the purification process.
Fortfahren mit
C2755
Kortison
synthetic, ≥95%, powder
Synonym(e):
17α,21-Dihydroxy-4-pregnen-3,11,20-trion, 17α-Hydroxy-11-dehydrocorticosteron, 4-Pregnen-17α,21-diol-3,11,20-trion
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| Größe/SKU | Verfügbarkeit | Preis |
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Über diesen Artikel
Empirische Formel (Hill-System):
C21H28O5
CAS-Nummer:
Molekulargewicht:
360.44
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
EC Number:
200-162-4
MDL number:
Beilstein/REAXYS Number:
1356062
Assay:
≥95%
Form:
powder
Preise und Verfügbarkeit sind derzeit nicht verfügbar.
Technischer Dienst
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Unterstützung erhaltenProduktname
Kortison, ≥95%
biological source
synthetic
Quality Segment
sterility
non-sterile
assay
≥95%
form
powder
technique(s)
inhibition assay: suitable
mp
223-228 °C (dec.) (lit.)
solubility
chloroform: methanol (1:1): 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow
shipped in
ambient
storage temp.
room temp
SMILES string
C[C@]12CCC(=O)C=C1CC[C@H]3[C@@H]4CC[C@](O)(C(=O)CO)[C@@]4(C)CC(=O)[C@H]23
InChI
1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-15,18,22,26H,3-8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1
InChI key
MFYSYFVPBJMHGN-ZPOLXVRWSA-N
Gene Information
human ... SERPINA6(866)
Application
Biochem/physiol Actions
Cortisone (11 dehydro 17 hydroxycortico-sterone) is an anti-inflammatory glucocorticoid that delays wound healing after surgeries. It postpones the healing process by affecting the appearance of inflammatory cells, ground substance, fibroblasts, collagen, regenerating capillaries, and epithelial migration. Glucocorticoids have anti-inflammatory, anti-allergic and immunosuppressive properties and are extensively used in treatment and therapy.
Cortisone is a glucocorticoid; a corticosterone analog that has approximately twice the anti-inflammatory potency as corticosterone but much lower Na2+ retention potency.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
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Dieser Artikel | |||
|---|---|---|---|
| description ≥95% | description United States Pharmacopeia (USP) Reference Standard | description Pharmaceutical Secondary Standard; Certified Reference Material | description certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland |
| form powder | form - | form - | form - |
| assay ≥95% | assay - | assay - | assay - |
| technique(s) inhibition assay: suitable | technique(s) - | technique(s) - | technique(s) gas chromatography (GC): suitable |
| Quality Level 200 | Quality Level - | Quality Level 300 | Quality Level 300 |
| storage temp. room temp | storage temp. −20°C | storage temp. -10 to -25°C | storage temp. 2-8°C |
| solubility chloroform: methanol (1:1): 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow | solubility - | solubility - | solubility - |
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Signalwort
Warning
Gefahrencodes
Sicherheitshinweise
Hazard Classifications
Repr. 2
Lagerklasse
11 - Combustible Solids
Was ist los?
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
PSA (Persönliche Schutzausrüstung)
Eyeshields, Gloves, type N95 (US)
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What kind of impurities this product consists? According assays it is ≥95% cortisone. What compounds are included in remaining 5%?
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