C5259

Carbamyl-β-Methylcholinchlorid

≥99% (TLC), crystalline

• Synonym(e): Bethanechol chloride
• Lineare Formel: C₇H₁₇N₂O₂Cl
• CAS-Nummer: 590-63-6
• Molekulargewicht: 196.68
• NACRES: NA.25
• PubChem Substance ID: 24277823
• UNSPSC Code: 41116107
• EC Number: 209-686-8
• MDL number: MFCD00055224

Eigenschaften

• InChI key: AIRHOJQHGLTTTB-UHFFFAOYSA-N
• InChI: 1S/C7H17N2O2.ClH/c1-6(11-7(8)10)5-9(2,3)4;/h6H,5H2,1-4H3,(H2,8,10);1H
• SMILES string: Cl.CC(C[N](C)(C)C)OC(N)=O
• assay: ≥99% (TLC)
• form: crystalline
• color: white
• solubility: H₂O: 1.7 g/mL (stable for several days at 4°C.), ethanol: 80 mg/mL (stable for several days at 4°C.)
• storage temp.: 2-8°C
• Quality Level: 100

Beschreibung

General description

Muscarinic acetylcholine receptor agonist that is not a substrate for acetylcholinesterase.

Application

Carbamyl-β-methylcholine chloride has been used in western blotting and bactericidal assay.[1] It has also been used in concentration-response studies with isolated atrial preparation.[2]

Biochem/physiol Actions

Carbamyl-β-methylcholine has a selective action on urinary bladder and intestine.[3] It induces smooth muscle tension in the bladder.[4] Its main function is to induce detrusor muscle action, mediated by postganglionic parasympathetic effector cells.[5] Nausea, flushing, sweating, abdominal cramps are some of the side effect caused by carbamyl-β-methylcholine.[6]

Disclaimer

Hygroscopic.

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves