Unless otherwise stated, this product is intended for research use only. It is not suitable for any other purpose, which includes, but is not limited to, unauthorized commercial use, in vitro diagnostic use, or therapeutic use in humans or animals.
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C8754
Thiaminpyrophosphat
≥95%, powder
Synonym(e):
Aneurinpyrophosphorsäure, Cocarboxylase
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| Größe/SKU | Verfügbarkeit | Preis |
|---|---|---|
1 g | Warenkorb auf Verfügbarkeit prüfen | € 67,10 |
5 g | Warenkorb auf Verfügbarkeit prüfen | € 97,40 |
25 g | Warenkorb auf Verfügbarkeit prüfen | € 376,00 |
100 g | Warenkorb auf Verfügbarkeit prüfen | € 1.030,00 |
Über diesen Artikel
Empirische Formel (Hill-System):
C12H19ClN4O7P2S
CAS-Nummer:
Molekulargewicht:
460.77
NACRES:
NA.54
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
205-836-1
MDL number:
Beilstein/REAXYS Number:
3875902
Technischer Dienst
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Unterstützung erhaltenProduktname
Thiaminpyrophosphat, ≥95%
Quality Segment
assay
≥95%
form
powder
solubility
H2O: soluble 50 mg/mL, clear to very slightly hazy, colorless
storage temp.
−20°C
SMILES string
CC1=C(CCOP(OP(O)(O)=O)(O)=O)SC=[N+]1CC2=C(N)N=C(C)N=C2.[Cl-]
InChI
1S/C12H18N4O7P2S.ClH/c1-8-11(3-4-22-25(20,21)23-24(17,18)19)26-7-16(8)6-10-5-14-9(2)15-12(10)13;/h5,7H,3-4,6H2,1-2H3,(H4-,13,14,15,17,18,19,20,21);1H
InChI key
YXVCLPJQTZXJLH-UHFFFAOYSA-N
Application
Thiamine pyrophosphate from Sigma has been used as a substrate to assay the enzymes in golgi lamellae isolated from rat tissue.
Thiamine pyrophosphate has been used:
- for the preparation of chitosan nano-particles
- as a standard for vitamin B1 and its derivative in high-performance
- liquid chromatography (HPLC) analysis
- immunofluorescence
Biochem/physiol Actions
Thiamine pyrophosphate (TPP) is a coenzyme of transketolase, that catalyzes the cleavage of ribulose-5-phosphate. This reaction leads to the formation of D-glyceraldehyde-3-phosphate. It requires the addition of an acceptor aldehyde such as ribose-5-phosphate, glyceraldehye or glycolaldehyde. TPP is capable of decarboxylating hydroxypyruvate in the presence of an ′acceptor aldehyde′.
1 of 1
Dieser Artikel | |||
|---|---|---|---|
| description ≥95% | description Pharmaceutical Secondary Standard; Certified Reference Material | description Inhibits ryanodine binding to ryanodine/Ca2+ receptor channel in skeletal muscle in a dose- and time-dependent manner and increases the Ca2+ permeability of SR vesicles. | description 96% (NT) |
| assay ≥95% | assay - | assay ≥97% (titration) | assay 96% (NT) |
| solubility H2O: soluble 50 mg/mL, clear to very slightly hazy, colorless | solubility - | solubility chloroform: soluble, ethanol: soluble | solubility - |
| Quality Level 200 | Quality Level 300 | Quality Level 100 | Quality Level 200 |
| form powder | form - | form liquid | form liquid |
| storage temp. −20°C | storage temp. -10 to -25°C | storage temp. 2-8°C | storage temp. 2-8°C |
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Signalwort
Warning
Gefahrencodes
Sicherheitshinweise
Hazard Classifications
Skin Sens. 1
Lagerklasse
11 - Combustible Solids
Was ist los?
WGK 1
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
PSA (Persönliche Schutzausrüstung)
Eyeshields, Gloves, type N95 (US)
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