The concentration is expressed as weight/volume (w/v). The exact concentration is provided on the lot-specific certificate of analysis (COA).
Fortfahren mit
C9394
Chlorhexidin -digluconat -Lösung
20% in H2O
Synonym(e):
1,6-Bis(N5-[p-chlorphenyl]-N1-biguanid)hexan; 1,1′-Hexamethylenbis(5-[p-chlorphenyl]biguanid)
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| Größe/SKU | Verfügbarkeit | Preis |
|---|---|---|
25 mL | Warenkorb auf Verfügbarkeit prüfen | € 109,00 |
100 mL | Warenkorb auf Verfügbarkeit prüfen | € 263,00 |
500 mL | Warenkorb auf Verfügbarkeit prüfen | € 862,00 |
Über diesen Artikel
CAS-Nummer:
NACRES:
NA.85
PubChem Substance ID:
UNSPSC Code:
51102829
MDL number:
Technischer Dienst
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Unterstützung erhaltenform
liquid
Quality Segment
concentration
20% in H2O
solubility
water: soluble 50 % (w/v)
density
1.06 g/mL at 25 °C (lit.)
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria
mode of action
cell membrane | interferes
storage temp.
2-8°C
SMILES string
OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.Clc1ccc(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(Cl)cc2)cc1
InChI
1S/C22H30Cl2N10.2C6H12O7/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18;2*7-1-2(8)3(9)4(10)5(11)6(12)13/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34);2*2-5,7-11H,1H2,(H,12,13)/t;2*2-,3-,4+,5-/m.11/s1
InChI key
YZIYKJHYYHPJIB-UUPCJSQJSA-N
Application
Chlorhexidin wurde genutzt, um die aseptische Wirkung von ätherischen Ölen in Kombination mit Chlorhexidindigluconat auf der Haut zu untersuchen und findet Verwendung in Studien zum Eindringen von Wirkstoffen in die Haut. Regelmäßige Chlorhexidinspülungen verringern nachweislich die Salzigkeit von NaCl und die Bitterkeit von Quinin.
Zur Untersuchung des membranschädigenden Mechanismus von Bis(biguanid)-Molekülen.
Biochem/physiol Actions
Kationisches antimikrobielles Mittel mit Breitbandwirkung aus der Familie der Biguanide. Sein Wirkmechanismus beruht auf einer Destabilisierung der bakteriellen Außenmembran. Es wird hauptsächlich als topisches Antiseptikum/Desinfektionsmittel in der Wundheilung, an Katheterisierungsstellen, in verschiedenen zahnmedizinischen Anwendungen und in Operationsoberbekleidung verwendet.
Other Notes
Behälter dicht verschlossen an einem trockenen und gut gelüfteten Ort aufbewahren. Geöffnete Behälter müssen sorgfältig wieder verschlossen und aufrecht gelagert werden, um Leckagen zu verhindern. Lichtempfindlich.
1 of 1
Dieser Artikel | |||
|---|---|---|---|
| description 20% in H2O | description Pharmaceutical Secondary Standard; Certified Reference Material | description ≥98% | description European Pharmacopoeia (EP) Reference Standard |
| mode of action cell membrane | interferes | mode of action - | mode of action - | mode of action - |
| antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria | antibiotic activity spectrum - | antibiotic activity spectrum - | antibiotic activity spectrum - |
| Quality Level 200 | Quality Level 300 | Quality Level 100 | Quality Level - |
| form liquid | form - | form powder | form - |
| solubility water: soluble 50 % (w/v) | solubility - | solubility - | solubility - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. - |
Signalwort
Danger
Gefahrencodes
Sicherheitshinweise
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1
Lagerklasse
12 - Non Combustible Liquids
Was ist los?
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
PSA (Persönliche Schutzausrüstung)
Eyeshields, Faceshields, Gloves, multi-purpose combination respirator cartridge (US)
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Is the 20% chlorhexidine digluconate (C9394) calculated as weight/weight (w/w) or weight/volume (w/v)? Because the specific gravity is given as 1.06 g/mL, this matters for calculating the molar concentration.
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How can I determine the shelf life / expiration / retest date of this product?
1 answer-
If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdfHelpful?
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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Hi, Is this pharma grade ? Kidn regards Archana
1 answer-
No, this product is not pharmaceutical grade. It is intended for research use only. Currently, a pharmaceutical grade of this material is not available.
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