If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
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For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
E4268
(−)-Epigallokatechingallat
≥80% (HPLC), from green tea
Synonym(e):
(−)-cis-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-gallat, (−)-cis-3,3′,4′,5,5′,7-Hexahydroxy-Flavan-3-Gallat, EGCG
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€ 83,20
Über diesen Artikel
Fortfahren mit
Biologische Quelle
green tea
Assay
≥80% (HPLC)
Anwendung(en)
metabolomics
vitamins, nutraceuticals, and natural products
Lagertemp.
2-8°C
SMILES String
Oc1cc(O)c2C[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](Oc2c1)c4cc(O)c(O)c(O)c4
InChI
1S/C22H18O11/c23-10-5-12(24)11-7-18(33-22(31)9-3-15(27)20(30)16(28)4-9)21(32-17(11)6-10)8-1-13(25)19(29)14(26)2-8/h1-6,18,21,23-30H,7H2/t18-,21-/m1/s1
InChIKey
WMBWREPUVVBILR-WIYYLYMNSA-N
Angaben zum Gen
human ... CYP1A2(1544)
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Dieser Artikel | E4143 | 324880 | PHR1333 |
|---|---|---|---|
| biological source green tea | biological source - | biological source - | biological source - |
| assay ≥80% (HPLC) | assay ≥95% | assay ≥95% (HPLC) | assay - |
| application(s) metabolomics | application(s) metabolomics | application(s) - | application(s) pharmaceutical (small molecule) |
| Quality Level 200 | Quality Level 200 | Quality Level 100 | Quality Level 300 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C | storage temp. 2-8°C |
| Gene Information human ... CYP1A2(1544) | Gene Information human ... CYP1A2(1544) | Gene Information - | Gene Information - |
Allgemeine Beschreibung
Anwendung
- a potential neuroprotective agent to test its protective effect against spinal cord injury and blood-spinal cord barrier (BSCB) leakage[2]
- an effective antioxidant against light-induced photoreceptor degeneration in mice retina[3]
- an antioxidant in retinitis pigmentosa (RP) and reduces oxidative damage and changes circadian rhythms in pigmented heterozygous P23H rat[4]
- to test its reversal effect on Diastolic dysfunction in restrictive cardiomyopathy (RCM) mice[5]
- an anti-cancer agent in colorectal cancer in mice[6]
Biochem./physiol. Wirkung
Signalwort
Warning
H-Sätze
Gefahreneinstufungen
Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 2
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
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Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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