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E7265
Big Endothelin 39 rat
≥97% (HPLC)
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| Größe/SKU | Verfügbarkeit | Preis |
|---|---|---|
0.1 mg | Warenkorb auf Verfügbarkeit prüfen | € 531,00 |
Über diesen Artikel
Empirische Formel (Hill-System):
C192H292N50O58S5
CAS-Nummer:
Molekulargewicht:
4389.00
UNSPSC Code:
12352202
NACRES:
NA.32
MDL number:
Assay:
≥97% (HPLC)
Technischer Dienst
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Unterstützung erhaltenQuality Segment
assay
≥97% (HPLC)
UniProt accession no.
storage temp.
−20°C
Gene Information
rat ... Edn1(24323)
General description
Big endothelin-1 is a 39 amino acid peptide, which is synthesized and secreted by vascular smooth muscle and endothelium cells. It is produced as an inactive enzyme, and is cleaved and activated by serine and aspartic proteases and metalloproteinases. Activated form is called ET-1, which is a potent vasoconstrictor. ET-1 is also produced by the action of endothelin converting enzyme (ECE) on big-ET-1. In guinea pigs, big-ET-1 causes the release of prostanoids and thromboxanes.
Application
Biochem/physiol Actions
Precursor of Endothelin-1; vasoconstrictor activity appears to be due to its conversion to endothelin 1 by endothelin converting enzyme in the tissue.
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Dieser Artikel | |||
|---|---|---|---|
| description ≥97% (HPLC) | description ≥97% (HPLC), powder | description ≥97% (HPLC), powder | description ≥97% (HPLC), powder |
| assay ≥97% (HPLC) | assay ≥97% (HPLC) | assay ≥97% (HPLC) | assay ≥97% (HPLC) |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| Gene Information rat ... Edn1(24323) | Gene Information human ... EDN1(1906) | Gene Information human ... EDN2(1907) | Gene Information human ... EDN3(1908) |
| UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. |
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 1 Inhalation - Acute Tox. 1 Oral
Lagerklasse
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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