![[D-Ala2, N-Me-Phe4, Gly5-ol]-Enkephalin acetate salt ≥97% (HPLC)](/deepweb/assets/sigmaaldrich/product/structures/227/014/768064c2-9ae6-47bd-8550-e2aa5c3b61de/640/768064c2-9ae6-47bd-8550-e2aa5c3b61de.png)
![[D-Ala2, D-Leu5]-Enkephalin acetate salt ≥95% (HPLC)](/deepweb/assets/sigmaaldrich/product/structures/934/176/d990e568-42df-43e9-a231-da7a3d9d7687/640/d990e568-42df-43e9-a231-da7a3d9d7687.png)
![[Met5]Enkephalin -acetat (Salz) Hydrat ≥95.0% (HPLC), powder](/deepweb/assets/sigmaaldrich/product/structures/158/699/80b4b65b-7e48-49a2-ba61-4433cf1f375c/640/80b4b65b-7e48-49a2-ba61-4433cf1f375c.png)
![[D-Ala2]-Deltorphin II ≥97% (HPLC)](/deepweb/assets/sigmaaldrich/product/structures/289/271/db4c3fc4-8ba9-46ef-b214-158c9758871f/640/db4c3fc4-8ba9-46ef-b214-158c9758871f.png)
This compound can be dissolved in DMSO, where it should be soluble to a concentration of 30 mg/mL.
Fortfahren mit
E7384
[D-Ala2, N-Me-Phe4, Gly5-ol]-Enkephalin acetate salt
≥97% (HPLC), μ-opioid receptors agonist
Synonym(e):
DAGO, DAMGO, Tyr-D-Ala-Gly-N-methyl-Phe-Gly-ol
Anmelden zur Ansicht der Organisations- und Vertragspreise.
Größe auswählen
Ansicht ändern
| Ihnen/SKU | Verfügbarkeit | Preis |
|---|---|---|
1 mg | Warenkorb auf Verfügbarkeit prüfen | € 53,70 |
5 mg | Warenkorb auf Verfügbarkeit prüfen | € 175,00 |
10 mg | Warenkorb auf Verfügbarkeit prüfen | € 301,00 |
50 mg | Warenkorb auf Verfügbarkeit prüfen | € 1.200,00 |
Über diesen Artikel
Empirische Formel (Hill-System):
C26H35N5O6
CAS-Nummer:
Molekulargewicht:
513.59
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.32
MDL number:
Technischer Dienst
Benötigen Sie Hilfe? Unser Team von erfahrenen Wissenschaftlern ist für Sie da.
Unterstützung erhaltenProduktname
[D-Ala2, N-Me-Phe4, Gly5-ol]-Enkephalin acetate salt, ≥97% (HPLC)
Quality Segment
assay
≥97% (HPLC)
storage temp.
−20°C
SMILES string
CC(O)=O.C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C)[C@@H](Cc2ccccc2)C(=O)NCCO
InChI
1S/C26H35N5O6.C2H4O2/c1-17(30-25(36)21(27)14-19-8-10-20(33)11-9-19)24(35)29-16-23(34)31(2)22(26(37)28-12-13-32)15-18-6-4-3-5-7-18;1-2(3)4/h3-11,17,21-22,32-33H,12-16,27H2,1-2H3,(H,28,37)(H,29,35)(H,30,36);1H3,(H,3,4)/t17-,21+,22+;/m1./s1
InChI key
XZZYKCKUDLGXJA-NJUGUJQKSA-N
Gene Information
human ... OPRM1(4988)
mouse ... OPRM1(18390)
rat ... OPRM1(25601)
General description
[D-Ala2, N-Me-Phe4, Gly5-ol]-Enkephalin acetate salt or DAMGO is a full agonist of the μ-opioid receptor. μ-opioid receptor is encoded by the OPRM1 gene, which has a predominant expression in reward-processing areas of brain. It acts as a receptor for endogenous opioids such as β-endorphin, encephalin, as well as foreign opioids such as morphine, heroin, and methadone.
Application
[D-Ala2, N-Me-Phe4, Gly5-ol]-Enkephalin acetate salt or DAMGO has been used:
- for use as a positive control in the assay of G-protein activation with μ-opioid receptor, to assay the inhibition of cAMP inhibition by DAMGO
- for the determination of the suppression of contraction by opioid receptors
- to determine whether the peripheral application of DAMGO suppresses the hypertonic saline (HS)-induced masseter nociception in slightly anaesthetized rats
Biochem/physiol Actions
Enkephalin analog that is a selective agonist at μ-opioid receptors.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
1 of 1
Dieser Artikel | |||
|---|---|---|---|
| description ≥97% (HPLC) | description ≥95% (HPLC) | description ≥95.0% (HPLC), powder | description ≥97% (HPLC) |
| assay ≥97% (HPLC) | assay ≥95% (HPLC) | assay ≥95.0% (HPLC) | assay ≥97% (HPLC) |
| Quality Level 100 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| Gene Information human ... OPRM1(4988) | Gene Information human ... OPRD1(4985) | Gene Information human ... OPRD1(4985), OPRM1(4988) | Gene Information human ... OPRD1(4985), OPRK1(4986), OPRM1(4988) |
Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Hier finden Sie alle aktuellen Versionen:
Besitzen Sie dieses Produkt bereits?
In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.
-
DAMGO Acetate salt를 H2O에 녹이라고 되어있는데, 이를 DMSO에 녹여서 사용해도 괜찮을까요? Specification sheets says to dissolve DAMGO Acetate salt in H2O, is it okay to dissolve it in DMSO?
1 answer-
Helpful?
-