E8375

Eserin

• Synonym(e): Physostigmin
• Empirische Formel (Hill-System): C₁₅H₂₁N₃O₂
• CAS-Nummer: 57-47-6
• Molekulargewicht: 275.35
• EC Number: 200-332-8
• UNSPSC Code: 12352200
• PubChem Substance ID: 24277867
• Beilstein/REAXYS Number: 91230
• MDL number: MFCD00151090

Eigenschaften

• assay: ≥99% (HPLC)
• mp: 102-104 °C (lit.)
• SMILES string: [H][C@]12N(C)CC[C@@]1(C)c3cc(OC(=O)NC)ccc3N2C
• InChI: 1S/C15H21N3O2/c1-15-7-8-17(3)13(15)18(4)12-6-5-10(9-11(12)15)20-14(19)16-2/h5-6,9,13H,7-8H2,1-4H3,(H,16,19)/t13-,15+/m1/s1
• InChI key: PIJVFDBKTWXHHD-HIFRSBDPSA-N
• Gene Information: human ... ACHE(43), APP(351), BCHE(590) ; mouse ... Ache(11423), Bche(12038), Chrm1(12669) ; rat ... Ache(83817), Bche(65036), Chrm2(81645)

Beschreibung

Biochem/physiol Actions

Acetylcholinesterase Inhibitor, der die Blut-Hirn-Schranke passiert.

Inhibitor von Acetylcholinesterase der die Blut-Hirn-Schranke passiert und einen carbamylierten Enzymkomplex mit Acetylcholinesterase bilded, der nur langsam abgebaut wird.

Features and Benefits

This compound is featured on the Acetylcholine Receptors (Nicotinic) and Acetylcholine Synthesis and Metabolism pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Sicherheitshinweise

• pictograms: GHS06
• signalword: Danger
• hcodes: H300 + H330
• pcodes: P301 + P310 + P330 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
• Lagerklasse: 6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 3
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges