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H2779
HistoChoice® Clearing Agent
alternative to toluene and xylene
Nachhaltigkeitsmerkmale
Synonym(e):
dewaxing mixture for paraffin tissue sections
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| Größe/SKU | Verfügbarkeit | Preis |
|---|---|---|
1 L | Warenkorb auf Verfügbarkeit prüfen | € 91,80 |
Über diesen Artikel
NACRES:
NA.47
UNSPSC Code:
12171500
Technischer Dienst
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Unterstützung erhaltenQuality Segment
form
liquid
sustainability
Sustainability features
color
colorless
density
0.760-0.820 g/mL
application(s)
hematology
histology
tissue diagnostics
storage temp.
room temp
General description
HistoChoice® is a patented, complex mixture of agents that allow tissues to retain their structure, antigenic sites, and nucleic acid sites. It is a non-toxic, non-cross-linking fixative formulated to replace formaldehyde-based fixation. This formulation in non-citrus, contains no mercury, formaldehyde, or glutaraldehyde.
This product aligns with one or more of the 12 Principles of Green ChemistryThis product has Inherently Safer Chemistry, compared to the standard use of formalin for tissue processing.
This product aligns with one or more of the 12 Principles of Green ChemistryThis product has Inherently Safer Chemistry, compared to the standard use of formalin for tissue processing.
Application
HistoChoice® Clearing Agent has the following applications:
- It is suitable as an alternative to toluene and xylene for dewaxing paraffin tissue sections. Prepared slides are suitable for antibody probing applications and in situ hybridizations.
- It has been employed in a study to explain the recalcitrance of lignocellulosic plant cell walls to enzymatic degradation.
- It has been used to develop a novel method to improve sensitivity for the localization of miRNA and their target transcripts in plants.
- It has been used to study the correlation of cytoplasmic ADP-ribosylation levels with markers of patient outcome in human cancers.
Biochem/physiol Actions
Fixation with HistoChoice® works well in immunohistology applications where its non-cross-linking traits are conducive to epitope retrieval and identification by primary antibodies to extracellular matrix components.
Features and Benefits
- Non-toxic, non-carcinogenic, and odorless.
- Non-flammable.
- Preserves native antigenic and nucleic acid sites.
- Compatible with many organic mounting media.
- Dissolves wax faster and evaporates slower than xylene.
- Can be used in automated processors.
- Tissues retain their original structure.
Legal Information
HistoChoice is a registered trademark of Amresco, Inc.
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Dieser Artikel | |||
|---|---|---|---|
| description alternative to toluene and xylene | description - | description histological grade | description - |
| Quality Level 100 | Quality Level 200 | Quality Level 100 | Quality Level 100 |
| density 0.760-0.820 g/mL | density - | density 0.86 g/mL at 25 °C (lit.) | density - |
| greener alternative category | greener alternative category - | greener alternative category - | greener alternative category - |
| application(s) hematology | application(s) - | application(s) histology | application(s) hematology |
| greener alternative product characteristics Designing Safer Chemicals | greener alternative product characteristics - | greener alternative product characteristics - | greener alternative product characteristics - |
| color colorless | color - | color - | color - |
Signalwort
Danger
Gefahrencodes
Sicherheitshinweise
Hazard Classifications
Asp. Tox. 1
Lagerklasse
10 - Combustible liquids
Flammpunkt (°F)
141.8 °F
Flammpunkt (°C)
61 °C
PSA (Persönliche Schutzausrüstung)
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
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What is the pH of HistoChoice® Clearing Agent?
1 answer-
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Hi, I'm curious about the chemical components present in the HistoChoice xylene alternative. In section 3 of the SDS, it states that the component is solely HistoChoice™ Choice Clearing Agent. What exactly is that? Is it limonene-based like HistoClear?
1 answer-
HistoChoice is product of Amresco, Inc. The exact chemical composition is being withheld as proprietary by the supplier. The Safety Data Sheet does provide a list for some hazards to be aware of. The product does not contain benzenoid ring compounds, formaldehyde, glutaraldehyde, or mercury.
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Is HistoChoice Clearing Agent, product H2779, compatible with polycarbonate?
1 answer-
The supplier of HistoChoice Clearing Agent has reported no incompatibilities were observed when polycarbonate was exposed to HistoChoice Clearning Agent for at least 1 hour.
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What is the Department of Transportation shipping information for this product?
1 answer-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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