IgG3, Kappa from murine myeloma

Name: IgG3, Kappa from murine myeloma
Brand: SIGMA

clone DX, purified immunoglobulin, buffered aqueous solution

Synonym(e):

Mouse IgG3-κ

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UNSPSC Code:

12352203

NACRES:

NA.46

MDL number:

MFCD00164803

Conjugate:

unconjugated

Clone:

DX, monoclonal

Application:

—

Citations:

Technischer Dienst

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Eigenschaften

biological source

mouse

Quality Segment

200

conjugate

unconjugated

antibody form

purified immunoglobulin

clone

DX, monoclonal

assay

≥95% (microfluidic capillary gel electrophoresis)

form

buffered aqueous solution

shipped in

dry ice

storage temp.

−20°C

Beschreibung

General description

IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections. IgG3 is the has a unique extended hinge region conferring greater flexibility
IgG3, κ from murine myeloma specifically recognizes mouse IgG3. Specificity of the mouse IgG3, κ is determined by immunodiffusion and IEP techniques. The purified myeloma preparation is non-reactive with antisera to mouse IgA, IgM, IgD, IgG1, IgG2a and IgG2b.

Application

IgG3, κ from murine myeloma was used as blocking agent in immunofluorescence labeling of larval and adult Echinococcus multilocularis worms. It was used as negative control in assay to study the surface binding of antibodies to meningococci.

Physical form

Solution in Tris buffered saline, pH 7.2, containing 0.1% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.