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MSTUD0175
MISSION® Synthetic microRNA Inhibitor, Mouse
mmu-miR-19b-3p
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NACRES:
NA.51
UNSPSC Code:
41105324
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Technischer Dienst
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Unterstützung erhaltenQuality Segment
product line
MISSION®
form
solid
mature sequence
UGUGCAAAUCCAUGCAAAACUGA
Sanger mature/minor accession no.
microRNA accession no.
MI0000718
storage temp.
−20°C
General description
Individual synthetic microRNA inhibitors were designed using a proprietary algorithm, which is based on the work of Haraguchi, T, et al. and in collaboration with Dr. Hideo Iba, University of Tokyo. This algorithm utilizes the tough decoy (TuD) design. miRNA are known to regulate gene expression in a variety of manners, including translational repression, mRNA cleavage and deadenylation.
The MISSION synthetic miRNA Inhibitors are small, double-stranded RNA molecules designed to inhibit a specific mature miRNA. The miRNA inhibitors were designed using the mature miRNA sequence information from miRBase and are 2′-O-methylated RNA duplexes with a miRNA binding site on each strand. Optimal miRNA inhibition is provided after transfection due to the robust secondary structure of the inhibitor.
Two negative controls are available: Arabidopsis thaliana sequence (NCSTUD001) and Caenorhabditis elegans sequence (NCSTUD002)
The MISSION synthetic miRNA Inhibitors are small, double-stranded RNA molecules designed to inhibit a specific mature miRNA. The miRNA inhibitors were designed using the mature miRNA sequence information from miRBase and are 2′-O-methylated RNA duplexes with a miRNA binding site on each strand. Optimal miRNA inhibition is provided after transfection due to the robust secondary structure of the inhibitor.
- Long lasting inhibition at very low dosage
- Excellent resistance to cellular nucleases
- Custom synthesis available for a variety of species
Two negative controls are available: Arabidopsis thaliana sequence (NCSTUD001) and Caenorhabditis elegans sequence (NCSTUD002)
Other Notes
Based on miRBase V19
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
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Dieser Artikel | |||
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| description mmu-miR-19b-3p | description mmu-miR-19a-3p | description mmu-miR-146a-5p | description mmu-miR-144-3p |
| mature sequence UGUGCAAAUCCAUGCAAAACUGA | mature sequence UGUGCAAAUCUAUGCAAAACUGA | mature sequence UGAGAACUGAAUUCCAUGGGUU | mature sequence UACAGUAUAGAUGAUGUACU |
| Sanger mature/minor accession no. | Sanger mature/minor accession no. | Sanger mature/minor accession no. | Sanger mature/minor accession no. |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| microRNA accession no. MI0000718 | microRNA accession no. MI0000688 | microRNA accession no. MI0000170 | microRNA accession no. MI0000168 |
| product line MISSION® | product line MISSION® | product line MISSION® | product line MISSION® |
| form solid | form solid | form solid | form solid |
signalword
Warning
hcodes
pcodes
Hazard Classifications
STOT RE 2 Inhalation
target_organs
Respiratory Tract
Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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