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N8652

NF 023 hydrate

Name: NF 023 hydrate
Brand: SIGMA
Price: 156.4 EUR

≥98% (HPLC), solid

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Synonym(e):

8,8′-[Carbonylbis(imino-3,1-phenylene carbonylimino)]bis(1,3,5-naphthalene-trisulfonic acid) hexasodium salt hydrate

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Größe/SKU	Verfügbarkeit	Preis
10 mg	Warenkorb auf Verfügbarkeit prüfen	€ 184,00 € 156,40
50 mg	Warenkorb auf Verfügbarkeit prüfen	€ 593,00

Über diesen Artikel

Empirische Formel (Hill-System):

C₃₅H₂₀N₄O₂₁S₆ · 6Na · xH₂O

CAS-Nummer:

104869-31-0

Molekulargewicht:

1162.88 (anhydrous basis)

NACRES:

NA.77

PubChem Substance ID:

24278597

UNSPSC Code:

12352200

MDL number:

MFCD11046019

Assay:

≥98% (HPLC)

Form:

solid

Storage condition:

desiccated

€ 156,40

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Eigenschaften

Quality Segment

100

assay

≥98% (HPLC)

form

solid

storage condition

desiccated

color

white to off-white

solubility

H₂O: >20 mg/mL

SMILES string

O.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[O-]S(=O)(=O)c1cc(c2c(NC(=O)c3cccc(NC(=O)Nc4cccc(c4)C(=O)Nc5ccc(c6cc(cc(c56)S([O-])(=O)=O)S([O-])(=O)=O)S([O-])(=O)=O)c3)ccc(c2c1)S([O-])(=O)=O)S([O-])(=O)=O

InChI

1S/C35H26N4O21S6.6Na.H2O/c40-33(38-25-7-9-27(63(49,50)51)23-13-21(61(43,44)45)15-29(31(23)25)65(55,56)57)17-3-1-5-19(11-17)36-35(42)37-20-6-2-4-18(12-20)34(41)39-26-8-10-28(64(52,53)54)24-14-22(62(46,47)48)16-30(32(24)26)66(58,59)60;;;;;;;/h1-16H,(H,38,40)(H,39,41)(H2,36,37,42)(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54)(H,55,56,57)(H,58,59,60);;;;;;;1H2/q;6*+1;/p-6

InChI key

FLINBQMOKZJBEC-UHFFFAOYSA-H

Gene Information

human ... P2RX1(5023), P2RY1(5028), P2RY11(5032), P2RY2(5029)

Beschreibung

Application

NF 023 hydrate has been used as an inhibitor of methyltransferases. It has also been used to test its inhibitory effect on human adenovirus type-37 (HAdV-D37) viral infection in human corneal epithelial (HCE) cells.

Biochem/physiol Actions

NF 023 contains six benzene rings and is a suramin analog. It is a potent, competitive, and selective P2X purinoceptor antagonist that aids in discriminating between P2X receptor subtypes.

Features and Benefits

This compound is featured on the P2 Receptors: P2X Ion Channel Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

Desiccate

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Dieser Artikel	P0021	480415	S7198
Sigma-Aldrich N8652 NF 023 hydrate	Sigma-Aldrich P0021 Pantoprazole sodium hydrate	Sigma-Aldrich 480415 NF023	Sigma-Aldrich S7198 Sivelestat sodium salt hydrate
description ≥98% (HPLC), solid	description ≥98% (HPLC)	description A suramin analog that acts as a selective and direct G-protein antagonist for α-subunits of the Go/Gi group (EC₅₀ ~ 300 nM).	description ≥98% (HPLC), solid
form solid	form powder	form solid	form solid
assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay ≥95% (HPLC)	assay ≥98% (HPLC)
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
solubility H₂O: >20 mg/mL	solubility H₂O: ≥20 mg/mL	solubility water: soluble	solubility DMSO: 10 mg/mL, clear
storage condition desiccated	storage condition desiccated	storage condition OK to freeze, desiccated (hygroscopic)	storage condition -
color white to off-white	color white to off-white	color white to off-white	color white to off-white