Q0632

Quinapril -hydrochlorid

≥98% (HPLC), solid

• Synonym(e): (3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isochinolincarbonsäure -hydrochlorid
• Empirische Formel (Hill-System): C₂₅H₃₀N₂O₅ · HCl
• CAS-Nummer: 82586-55-8
• Molekulargewicht: 474.98
• NACRES: NA.77
• PubChem Substance ID: 329823858
• UNSPSC Code: 41116107
• MDL number: MFCD00889215
• eCl@ss: 32120505
• Assay: ≥98% (HPLC)
• Form: solid

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: solid
• color: white
• solubility: H₂O: >10 mg/mL
• storage temp.: 2-8°C
• SMILES string: Cl.CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N2Cc3ccccc3C[C@H]2C(O)=O
• InChI: 1S/C25H30N2O5.ClH/c1-3-32-25(31)21(14-13-18-9-5-4-6-10-18)26-17(2)23(28)27-16-20-12-8-7-11-19(20)15-22(27)24(29)30;/h4-12,17,21-22,26H,3,13-16H2,1-2H3,(H,29,30);1H/t17-,21-,22-;/m0./s1
• InChI key: IBBLRJGOOANPTQ-JKVLGAQCSA-N
• Gene Information: human ... ACE(1636)

Beschreibung

Application

Quinapril hydrochloride has been used as an angiotensin-converting enzyme (ACE) inhibitor to study its effects on renal tubular epithelial cell proliferation in human renal tubular epithelial cells. It has also been used as an ACE inhibitor to evaluate its effects on the expression of angiotensin II (AII) in patient-derived Atheroma samples.

Biochem/physiol Actions

Quinapril has been studied to exhibit therapeutic effects against hypertension and congestive heart failure.

Quinapril ist ein kurz wirkender ACE(Angiotensin-konvertierendes Enzym)-Hemmer.

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Danger
• Gefahrencodes: H361d,H372
• Sicherheitshinweise: P202 - P260 - P264 - P280 - P308 + P313 - P405
• Hazard Classifications: Repr. 2 - STOT RE 1
• Lagerklasse: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): Eyeshields, Gloves, type N95 (US)