RAB0244

Human IL-10 ELISA Kit

• Synonym(e): IL-10, Interleukin-10
• NACRES: NA.32
• UNSPSC Code: 41116158
• Gene information: human ... IL10(3586)
• Input: sample type serum; sample type cell culture supernatant(s); sample type plasma
• Species reactivity: human
• Storage temp.: −20°C
• Shipped in: wet ice

Eigenschaften

• species reactivity: human
• packaging: kit of 96 wells (12 strips x 8 wells)
• technique(s): ELISA: suitable, capture ELISA: suitable
• input: sample type serum; sample type cell culture supernatant(s); sample type plasma
• detection method: colorimetric
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... IL10(3586)

Beschreibung

General description

Interleukin-10 (IL-10) is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells and B cells. Murine IL-10 is inactive on human cells. The gene encoding this protein is localized on human chromosome 1q31-32.

Immunogen

Recombinant Human IL-10

Application

For research use only. Not for use in diagnostic procedures.
Human IL-10 ELISA kit has been used for determining the levels of IL-10 in cell culture supernatant.

Human IL-10 ELISA Kit has been used in enzyme-linked immunosorbent assay (ELISA) to detect interleukin-10 (IL-10) in the plasma of uremic patients undergoing hemodialysis (HD).

Biochem/physiol Actions

IL-10 (interleukin 10) is an anti-inflammatory cytokine. IL-10 inhibits the expression of proinflammatory cytokines such as IL-1 and TNF (tumor necrosis factor)-α. Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions. Polymorphisms in the IL-10 gene are associated with higher risk of preeclampsia, ankylosing spondylitis, nasopharyngeal carcinoma and basal cell carcinoma. Polymorphism in IL-10 at -1082A/G is associated with diabetic nephropathy.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Danger
• Gefahrencodes: H334
• Sicherheitshinweise: P261 - P284 - P501
• Hazard Classifications: Resp. Sens. 1
• Lagerklasse: 10 - Combustible liquids