Fortfahren mit
S0693
SB 204741
>98% (HPLC)
Synonym(e):
N-(1-Methyl-1H-5-indolyl)-N′-(3-methyl-5-isothiazolyl)urea
Größe auswählen
| Größe/SKU | Verfügbarkeit | Preis |
|---|---|---|
10 mg | Warenkorb auf Verfügbarkeit prüfen | € 213,00 |
50 mg | Warenkorb auf Verfügbarkeit prüfen | € 983,00 |
Über diesen Artikel
Quality Segment
assay
>98% (HPLC)
form
solid
color
off-white to tan
solubility
DMSO: soluble >20 mg/mL
originator
GlaxoSmithKline
storage temp.
2-8°C
SMILES string
Cc1cc(NC(=O)Nc2ccc3n(C)ccc3c2)sn1
InChI
1S/C14H14N4OS/c1-9-7-13(20-17-9)16-14(19)15-11-3-4-12-10(8-11)5-6-18(12)2/h3-8H,1-2H3,(H2,15,16,19)
InChI key
USFUFHFQWXDVMH-UHFFFAOYSA-N
Gene Information
human ... DRD2(1813), DRD3(1814), DRD5(1816), HTR1E(3354), HTR2A(3356), HTR2B(3357), HTR2C(3358)
rat ... Adra1a(29412), Gabra2(29706), Htr1a(24473), Htr2b(29581), Htr3a(79246)
Application
- to inhibit Htr2b signaling to test its effect on hepatic stellate cell (HSC) activation in three-month-old adult zebrafish
- to test its effect on the inhibition of fluoxetine effects in depressive-like behavioral studies in mice
- to test its effect in reducing scratching behavior evoked by sertraline in mice
Biochem/physiol Actions
Features and Benefits
Legal Information
1 of 1
Dieser Artikel | |||
|---|---|---|---|
| description >98% (HPLC) | description InSolution, ≥98%, p38 MAP kinase inhibitor | description SB 202190, CAS 152121-30-7, is a potent, reversible, competitive inhibitor of p38. Inhibits p38 phosphorylation of myelin basic protein. Blocks the activity of p38β (Ki = 16 nM; IC50 = 350 nM). | description InSolution, ≥98%, 1 mg/ml, reversible inhibitor of p38 MAP kinase |
| form solid | form liquid | form solid | form liquid |
| assay >98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| solubility DMSO: soluble >20 mg/mL | solubility - | solubility DMSO: 50 mg/mL | solubility - |
| color off-white to tan | color - | color pale yellow | color - |
Signalwort
Warning
Gefahrencodes
Sicherheitshinweise
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Zielorgane
Respiratory system
Lagerklasse
11 - Combustible Solids
Was ist los?
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
PSA (Persönliche Schutzausrüstung)
dust mask type N95 (US), Eyeshields, Gloves
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