S1875

(−)-Scopolamin -hydrobromid Trihydrat

>95% (HPLC), muscarinic acetylcholine antagonist, powder

• Synonym(e): Hyoscin -hydrobromid, Scopin-tropat
• Empirische Formel (Hill-System): C₁₇H₂₁NO₄ · HBr · 3H₂O
• CAS-Nummer: 6533-68-2
• Molekulargewicht: 438.31
• NACRES: NA.77
• PubChem Substance ID: 24277871
• UNSPSC Code: 12352116
• MDL number: MFCD00150066
• Beilstein/REAXYS Number: 6100669
• Assay: >95% (HPLC)
• Form: powder

Eigenschaften

• Produktname: (−)-Scopolamin -hydrobromid Trihydrat, >95% (HPLC), powder
• Quality Segment: 200
• assay: >95% (HPLC)
• form: powder
• optical activity: [α]25/D −23 to −27°, c = 5 in H₂O(lit.)
• color: white to off-white
• mp: 195-199 °C (dry matter) (lit.)
• solubility: H₂O: 50 mg/mL
• SMILES string: O.O.O.Br.CN1[C@@H]2C[C@H](C[C@H]1[C@@H]3O[C@H]23)OC(=O)[C@H](CO)c4ccccc4
• InChI: 1S/C17H21NO4.BrH.3H2O/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;;;;/h2-6,11-16,19H,7-9H2,1H3;1H;3*1H2/t11-,12-,13-,14+,15-,16+;;;;/m1..../s1
• InChI key: LACQPOBCQQPVIT-SEYKEWMNSA-N
• Gene Information: human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)

Beschreibung

Biochem/physiol Actions

Kompetitiver, nichtselektiver muskarinischer Acetylcholin-Antagonist. Scopolamin-induzierte Amnesie bei Labortieren ist ein häufig verwendetes Modell von Gedächtnis-Defizit.

Competitive nonselective muscarinic acetylcholine antagonist.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• Gefahrencodes: H300 + H310 + H330
• Hazard Classifications: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
• Lagerklasse: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
• Sicherheitshinweise: P262 - P264 - P280 - P301 + P310 + P330 - P302 + P352 + P310 - P304 + P340 + P310