This product is slightly soluble in water at < 1mg/mL. Other solvents include DMSO, DMF, and Acetone at approximately 50 mg/mL.
Fortfahren mit
S6256
Sulfamethazin
99.0-101.0% (on dried basis)
Synonym(e):
4,6-Dimethylsulfadiazin, 4-Amino-N-(4,6-dimethyl-2-pyrimidinyl)-benzolsulfonamid, Sulfadimethyldiazin, Sulfadimidin
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| Größe/SKU | Verfügbarkeit | Preis |
|---|---|---|
25 g | Warenkorb auf Verfügbarkeit prüfen | € 54,20 |
100 g | Warenkorb auf Verfügbarkeit prüfen | € 96,90 |
Über diesen Artikel
Empirische Formel (Hill-System):
C12H14N4O2S
CAS-Nummer:
Molekulargewicht:
278.33
UNSPSC Code:
51284910
NACRES:
NA.85
PubChem Substance ID:
EC Number:
200-346-4
Beilstein/REAXYS Number:
261304
MDL number:
Technischer Dienst
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Unterstützung erhaltenQuality Segment
assay
99.0-101.0% (on dried basis)
form
powder or crystals
storage condition
(Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)
color
white to off-white
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria
mode of action
DNA synthesis | interferes, enzyme | inhibits
storage temp.
2-8°C
SMILES string
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
InChI
1S/C12H14N4O2S/c1-8-7-9(2)15-12(14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16)
InChI key
ASWVTGNCAZCNNR-UHFFFAOYSA-N
General description
Chemical structure: sulfonamide
Application
Biochem/physiol Actions
Sulfamethazine is an antimicrobial sulfur drug that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfamethazine is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. It induces CYP3A4 expression and is acetylated by N-acetyltransferase. It exhibits sex dependent pharmacokinetics, metabolized by the male specific isoform CYP2C11. Sulfamethazine is bacteriostatic.
Ein antimikrobieller Schwefelwirkstoff. Induziert die CYP3A4-Expression und wird acetyliert durch N-Acetyltransferase. Weist geschlechtsabhängige Pharmakokinetik auf, metabolisiert durch die maskuline Isofrom CYP2C11.
Packaging
25G,100G
Other Notes
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
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Dieser Artikel | |||
|---|---|---|---|
| description 99.0-101.0% (on dried basis) | description pharmaceutical secondary standard, certified reference material | description VETRANAL®, analytical standard | description European Pharmacopoeia (EP) Reference Standard |
| antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria | antibiotic activity spectrum - | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria | antibiotic activity spectrum - |
| mode of action DNA synthesis | interferes, enzyme | inhibits | mode of action - | mode of action DNA synthesis | interferes, enzyme | inhibits | mode of action - |
| Quality Level 200 | Quality Level 300 | Quality Level 200 | Quality Level - |
| assay 99.0-101.0% (on dried basis) | assay - | assay - | assay - |
| form powder or crystals | form - | form - | form - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. - | storage temp. 2-8°C |
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Lagerklasse
11 - Combustible Solids
PSA (Persönliche Schutzausrüstung)
Eyeshields, Gloves, type N95 (US)
Signalwort
Warning
Gefahrencodes
Sicherheitshinweise
Hazard Classifications
Skin Irrit. 2
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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Is Sulfamethazine (Product code: S6256) soluble in water of in any specific solvent. Please suggest.
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