Wichtige Dokumente

Gesamtdokumentation anzeigen

SML0004

(S)-(+)-Clopidogrel hydrogensulfate

Name: (S)-(+)-Clopidogrel hydrogensulfate
Brand: SIGMA

≥98% (HPLC), Selective P2Y12 antagonist, powder

Synonym(e):

(S)-(+)-Clopidogrel bisulfate, (S)-(+)-Methyl 2-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)-2-(2-chlorophenyl)acetate hydrogensulfate, Clopidogrel Bisulphate

Anmelden zur Ansicht der Organisations- und Vertragspreise.

Größe auswählen

Ansicht ändern

Über diesen Artikel

Empirische Formel (Hill-System):

C₁₆H₁₆ClNO₂S · H₂SO₄

CAS-Nummer:

120202-66-6

Molekulargewicht:

419.90

UNSPSC Code:

12352200

PubChem Substance ID:

329825081

NACRES:

NA.77

MDL number:

MFCD00876395

Assay:

≥98% (HPLC)

Form:

powder

Technischer Dienst

Benötigen Sie Hilfe? Unser Team von erfahrenen Wissenschaftlern ist für Sie da.

Unterstützung erhalten

Eigenschaften

Produktname

(S)-(+)-Clopidogrel hydrogensulfate, ≥98% (HPLC)

Quality Segment

100

assay

≥98% (HPLC)

form

powder

optical activity

[α]/D +54 to +70°, c = 0.5 in methanol

color

white to tan

solubility

DMSO: ≥20 mg/mL (warmed)

originator

Bristol-Myers Squibb, Sanofi Aventis

storage temp.

2-8°C

SMILES string

OS(O)(=O)=O.COC(=O)[C@@H](N1CCc2sccc2C1)c3ccccc3Cl

InChI

1S/C16H16ClNO2S.H2O4S/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-14-11(10-18)7-9-21-14;1-5(2,3)4/h2-5,7,9,15H,6,8,10H2,1H3;(H2,1,2,3,4)/t15-;/m0./s1

InChI key

FDEODCTUSIWGLK-RSAXXLAASA-N

Gene Information

human ... P2RY12(64805)

Beschreibung

Application

(S)-(+)-Clopidogrel hydrogensulfate was used as standard in HPLC-MS/MS to detect clopidogrel and its thiol derivative in human plasma.

Biochem/physiol Actions

(S)-(+)-Clopidogrel hydrogen sulfate is an antithrombotic antiplatelet agent.

(S)-(+)-Clopidogrel hydrogen sulfate is an antithrombotic antiplatelet agent. It specifically and irreversibly inhibits the Purinoceptor P2Y12 subtype which inhibits ADP-induced platelet aggregation. (S)-(+)-Clopidogrel hydrogen sulfate is the active isomer.

Features and Benefits

This compound is featured on the P2 Receptors: P2Y G-Protein Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Bristol-Myers Squibb and Sanofi Aventis. To browse the list of other pharma-developed compounds, Approved Drugs, and Drug Candidates, click here.