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SML0791

N,N-Dimethyltryptamine

Name: N,N-Dimethyltryptamine
Brand: SIGMA

≥97% (HPLC), Sigma-1 receptor agonist, powder

Synonym(e):

DMT, Dimethyltryptamine, N,N-Dimethyl-1H-indole-3-ethanamine

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Über diesen Artikel

Empirische Formel (Hill-System):

C₁₂H₁₆N₂

CAS-Nummer:

61-50-7

Molekulargewicht:

188.27

UNSPSC Code:

12352116

PubChem Substance ID:

329825600

NACRES:

NA.77

MDL number:

MFCD00055989

Assay:

≥97% (HPLC)

Form:

powder

Technischer Dienst

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Eigenschaften

Produktname

N,N-Dimethyltryptamine, ≥97% (HPLC)

Quality Segment

100

assay

≥97% (HPLC)

form

powder

drug control

USDEA Schedule I; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal); Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet, kontrollierte Droge in Deutschland

color

white to beige

solubility

DMSO: 15 mg/mL, clear

storage temp.

−20°C

SMILES string

CN(C)CCC1=CNC2=C1C=CC=C2

InChI

1S/C12H16N2/c1-14(2)8-7-10-9-13-12-6-4-3-5-11(10)12/h3-6,9,13H,7-8H2,1-2H3

InChI key

DMULVCHRPCFFGV-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

N,N-Dimethyltryptamine (DMT) is a hallucinogen now known to be an endogenous sigma-1 receptor agonist. In keeping with the known sigma-1 receptor modulation of voltage gated Na+ channels, DMT was found to reversibly inhibit Na currents by 62% in vitro. N,N-Dimethyltryptamine also induced hypermotility in WT mice (but not in sigma-1 KO mice), all evidence of its sigma-1 agonist activity.

N,N-Dimethyltryptamine is an endogenous sigma-1 receptor agonist; hallucinogen.

N,N-Dimethyltryptamine (DMT) functions as a hallucinogen. Experimental studies states that DMT is an endogenous sigma-1 receptor agonist. DMT interacts with sigma-1 receptors and blocks voltage-gated sodium ion (Na⁺) channels in both native cardiac myocytes and heterologous cells that contain sigma-1 receptors.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Other Notes

Product contains 1.2% wt. EtOH (by NMR and EA).

Legal Information

German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.