SML1606

Oseltamivirphosphat

≥98% (HPLC), Neuraminidase inhibitor, powder

• Synonym(e): (3R,4R,5S)-4-Acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexen-1-carbonsäure-ethylester -phosphat (Salz)
• Empirische Formel (Hill-System): C₁₆H₂₈N₂O₄ ·H₃PO₄
• CAS-Nummer: 204255-11-8
• Molekulargewicht: 410.40
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825492
• NACRES: NA.77
• MDL number: MFCD08059548
• eCl@ss: 32160703
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Produktname: Oseltamivirphosphat, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• optical activity: [α]/D -26 to -36°, c = 1 in H₂O
• color: white to beige
• solubility: H₂O: 30 mg/mL, clear
• storage temp.: −20°C
• SMILES string: OP(O)(O)=O.CCOC(=O)C1=C[C@@H](OC(CC)CC)[C@H](NC(C)=O)[C@@H](N)C1
• InChI: 1S/C16H28N2O4.H3O4P/c1-5-12(6-2)22-14-9-11(16(20)21-7-3)8-13(17)15(14)18-10(4)19;1-5(2,3)4/h9,12-15H,5-8,17H2,1-4H3,(H,18,19);(H3,1,2,3,4)/t13-,14+,15+;/m0./s1
• InChI key: PGZUMBJQJWIWGJ-ONAKXNSWSA-N

Beschreibung

Biochem/physiol Actions

Oseltamivir phosphate is an influenza viral neuraminidase inhibitor. Oseltamivir phosphate, an antiviral, is used clinically to treat influenza A and influenza B, and to prevent flu after exposure. Oseltamivir phosphate is hydrolyzed in the liver to its active form, oseltamivir carboxylate, which is an inhibitor of influenza viral neuraminidases essential for viral replication. Oseltamivir has a broad spectrum of activity against a range of influenza A and B subtypes with IC₅₀ values for neuraminidases measured from less than 1 nM to approximately 30 nM, depending on the virus subtype.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• Gefahrencodes: H317,H319,H412
• Sicherheitshinweise: P261 - P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Aquatic Chronic 3 - Eye Irrit. 2 - Skin Sens. 1
• Lagerklasse: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable