SML3181

7,8-Dimethoxyperphenazine

≥98% (HPLC)

• Synonym(e): 2-(4-(3-((3-chlorophenyl)(3,4-dimethoxyphenyl)amino)propyl)piperazin-1-yl)ethan-1-ol, 4-[3-[8-Chloro-2,3-dimethoxy-10H-phenothiazin-10-yl]propyl]-1-piperazineethanol
• Empirische Formel (Hill-System): C₂₃H₃₀ClN₃O₃S
• Molekulargewicht: 464.02
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: ClC1=CC=C2C(N(CCCN3CCN(CCO)CC3)C(C=C(C(OC)=C4)OC)=C4S2)=C1
• InChI key: GKWVWOUUPIERSK-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

7,8-Dimethoxyperphenazine is a cell penetrant inhibitor of UHM (U2AF homology motif) -ULM (U2AF ligand motif) interactions that interacts with the tryptophan binding pocket of different UHM domains including SPF45, PUF60 and U2AF. 7,8-Dimethoxyperphenazine inhibits early spliceosome assembly on pre-mRNA substrates in vitro.

cell penetrant inhibitor of UHM (U2AF homology motif) -ULM (U2AF ligand motif) interactions that interacts with the tryptophan binding pocket of UHM domains

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• Gefahrencodes: H302,H317
• Sicherheitshinweise: P261 - P264 - P270 - P280 - P301 + P312 - P302 + P352
• Hazard Classifications: Acute Tox. 4 Oral - Skin Sens. 1
• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable