Fortfahren mit
SML3475
PF-04965842
≥98% (HPLC)
Synonym(e):
Abrocitinib, N-[cis-3-(Methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclobutyl]-1-propanesulfonamide, N-{cis-3-[Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}-propane-1-sulfonamide, PF 04965842
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Über diesen Artikel
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
CN(C1=C2C(NC=C2)=NC=N1)[C@H]3C[C@H](C3)NS(=O)(CCC)=O
InChI
1S/C14H21N5O2S/c1-3-6-22(20,21)18-10-7-11(8-10)19(2)14-12-4-5-15-13(12)16-9-17-14/h4-5,9-11,18H,3,6-8H2,1-2H3,(H,15,16,17)/t10-,11+
InChI key
IUEWXNHSKRWHDY-PHIMTYICSA-N
Biochem/physiol Actions
1 of 1
Dieser Artikel | |||
|---|---|---|---|
| description ≥98% (HPLC) | description ≥95% | description ≥98% (HPLC) | description JAK Inhibitor I, CAS 457081-03-7, is a potent, reversible, cell-permeable, and ATP-competitive inhibitor of JAK 1 (IC50 = 15 nM), JAK2 (IC50 = 1 nM), JAK3 (Ki = 5 nM) and Tyk2 (IC50 = 1 nM). |
| assay ≥98% (HPLC) | assay ≥95% | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| form powder | form - | form powder | form solid |
| Quality Level 100 | Quality Level 100 | Quality Level - | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C |
| solubility DMSO: 2 mg/mL, clear | solubility - | solubility DMSO: 2 mg/mL, clear (warmed) | solubility DMSO: 5 mg/mL |
| color white to beige | color - | color white to beige | color off-white to light brown |
Signalwort
Warning
Gefahrencodes
Sicherheitshinweise
Hazard Classifications
Acute Tox. 4 Oral
Lagerklasse
11 - Combustible Solids
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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