SML3953

Istaroxime hydrochloride

≥98% (HPLC)

• Synonym(e): Androstane-3,6,17-trione, 3-[O-(2-aminoethyl)oxime], hydrochloride (1:1)
• Empirische Formel (Hill-System): C₂₁H₃₂N₂O₃·HCl
• CAS-Nummer: 374559-48-5
• Molekulargewicht: 396.95
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD26960953
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: -10 to -25°C

Beschreibung

Biochem/physiol Actions

Positive inotropic agent that inhibits Na + /K + -ATPase and increases activity of Ca 2+ -ATPase at the sarcoplasmic reticulum.



Istaroxime is a positive inotropic agent that inhibits Na + /K + -ATPase and increases activity of Ca 2+ -ATPase at the sarcoplasmic reticulum. It improves cardiac performance in the failing heart. Istaroxime ameliorates calcium dysregulation Zebrafish PLN R14del arrhythmogenic cardiomyopathy model.

Disclaimer

Hygroscopic

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Warning
• Gefahrencodes: H373
• Sicherheitshinweise: P260 - P314 - P501
• Hazard Classifications: STOT RE 2
• Zielorgane: Gastro-intestinal system,Heart
• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable