SML4087

Spns2 inhibitor 16d

≥98% (HPLC)

• Synonym(e): 3-(4-Decylphenyl)-1,2,4-oxadiazole-5-propanamine hydrochloride, SLF1081851
• Empirische Formel (Hill-System): C₂₁H₃₃N₃O·HCl
• CAS-Nummer: 2999629-35-3
• Molekulargewicht: 379.97
• UNSPSC Code: 41106300
• NACRES: NA.21
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: CCCCCCCCCCC1=CC=C(C=C1)C2=NOC(CCCN)=N2.Cl
• InChI: 1S/C21H33N3O.ClH/c1-2-3-4-5-6-7-8-9-11-18-13-15-19(16-14-18)21-23-20(25-24-21)12-10-17-22;/h13-16H,2-12,17,22H2,1H3;1H
• InChI key: ZJJXKBLUUGLWDW-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

Potent and selective inhibitor of Spns2 (spinster homolog 2) sphingosine-1-phosphate (SP1) transporter.
Spns2 inhibitor 16d (SLF1081851) is a potent and selective inhibitor of Spns2 (spinster homolog 2) sphingosine-1-phosphate (SP1) transporter. Spns2 inhibitor 16d (SLF1081851) decreases circulating plasma S1P and lymphocytes in mice and rats. Apparently, it locks Spns2 in the inward-facing state.

Disclaimer

Hygroscopic

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• Gefahrencodes: H302
• Sicherheitshinweise: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable