SML4401

5-TAMRA-PEG4-Alkyne

≥98% (HPLC)

• Synonym(e): 5-Carboxytetramethylrhodamine, PEG4-Propargylamide, 9-[2-Carboxy-4-(1-oxo-5,8,11,14-tetraoxa-2-azaheptadec-16-yn-1-yl)phenyl]-3,6-bis(dimethylamino)-xanthylium inner salt, TAMRA-PEG4-Alkyne, TAMRA-5-PEG4-Alkyne, TAMRA-PEG4-Alkyne 5-isomer, TAMRA-(PEG)4-alkyne
• Empirische Formel (Hill-System): C₃₆H₄₁N₃O₈
• CAS-Nummer: 1225057-68-0
• Molekulargewicht: 643.73
• UNSPSC Code: 12352200
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated, protect from light

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated, protect from light
• color: dark blue to very dark purple
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: -10 to -25°C

Beschreibung

Biochem/physiol Actions

5-TAMRA-PEG4-Alkyne (TAMRA-PEG4-Alkyne) is a high-precision bioorthogonal probe engineered for the specific, covalent labeling of azide-modified biomolecules. TAMRA-Alkyne integrates the bright, photostable 5-TAMRA fluorophore (λex/λem: ~555/580 nm) with a terminal alkyne for irreversible copper-catalyzed click chemistry. Its key strategic advantage lies in the bifunctional design, where an isomerically pure fluorophore ensures reproducibility and a hydrophilic PEG4 linker enhances aqueous solubility while minimizing non-specific background. This construct enables robust, high signal-to-noise visualization of metabolically incorporated tags in complex biological samples via microscopy and in-gel analysis, providing a versatile and reliable alternative to antibody-based detection methods for studying dynamic cellular processes.

Disclaimer

Hygroscopic, store with desiccant

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable