T3146

Trimipramin -maleat (Salz)

≥98% (TLC), serotonin transport blocker, powder

• Empirische Formel (Hill-System): C₂₀H₂₆N₂ · C₄H₄O₄
• CAS-Nummer: 521-78-8
• Molekulargewicht: 410.51
• NACRES: NA.77
• PubChem Substance ID: 24278731
• UNSPSC Code: 12352116
• EC Number: 208-318-3
• MDL number: MFCD00082376
• Assay: ≥98% (TLC)
• Form: powder

Eigenschaften

• Produktname: Trimipramin -maleat (Salz), ≥98% (TLC), powder
• Quality Segment: 200
• assay: ≥98% (TLC)
• form: powder
• color: white to off-white
• solubility: chloroform: soluble 50 mg/ml, clear, colorless to faintly yellow
• originator: Sanofi Aventis
• storage temp.: 2-8°C
• SMILES string: OC(=O)\C=C\C(O)=O.CC(CN(C)C)CN1c2ccccc2CCc3ccccc13
• InChI: 1S/C20H26N2.C4H4O4/c1-16(14-21(2)3)15-22-19-10-6-4-8-17(19)12-13-18-9-5-7-11-20(18)22;5-3(6)1-2-4(7)8/h4-11,16H,12-15H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1+
• InChI key: YDGHCKHAXOUQOS-WLHGVMLRSA-N
• Gene Information: human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363) ;

Beschreibung

Application

Trimipramine maleate has been used to develop chiral separation methods using capillary electrophoresis⁴.

Biochem/physiol Actions

Antidepressant; serotonin transport blocker that also blocks norepinephrine uptake.

Preparation Note

Trimipramine maleate is soluble in chloroform at 50 mg/ml to yield a clear, colorless to faint yellow solution.

Sicherheitshinweise

• Piktogramme: GHS08,GHS07
• Signalwort: Warning
• Gefahrencodes: H302,H315,H319,H335,H361
• Sicherheitshinweise: P202 - P261 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklasse: 11 - Combustible Solids
• WGK: WGK 3
• PSA (Persönliche Schutzausrüstung): Eyeshields, Gloves, type P3 (EN 143) respirator cartridges