T3577

Tolperisone -hydrochlorid

≥98% (HPLC), ion channel blocker , solid

• Synonym(e): 2-Methyl-1-(4-methylphenyl)-3-(1-piperidyl)propan-1-one -hydrochlorid
• Empirische Formel (Hill-System): C₁₆H₂₃NO · HCl
• CAS-Nummer: 3644-61-9
• Molekulargewicht: 281.82
• NACRES: NA.77
• PubChem Substance ID: 329826771
• UNSPSC Code: 12352200
• EC Number: 222-876-5
• MDL number: MFCD00058211
• Assay: ≥98% (HPLC)
• Form: solid
• Storage condition: desiccated

Eigenschaften

• Produktname: Tolperisone -hydrochlorid, ≥98% (HPLC), solid
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: solid
• storage condition: desiccated
• color: white
• solubility: H₂O: >20 mg/mL
• storage temp.: room temp
• SMILES string: Cl.CC(CN1CCCCC1)C(=O)c2ccc(C)cc2
• InChI: 1S/C16H23NO.ClH/c1-13-6-8-15(9-7-13)16(18)14(2)12-17-10-4-3-5-11-17;/h6-9,14H,3-5,10-12H2,1-2H3;1H
• InChI key: ZBUVYROEHQQAKL-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

Tolperisone is an ion channel blocker and centrally acting muscle relaxant.

Tolperisone regulates ionic currents in myelinates axons and subsequently decreases excitability and mediates its antispastic functions³.

Tolperisone is derived from piperidine and possesses membrane stabilizing action. It helps in reducing the effect of spasticities associated with the nervous and muscular system. It exhibits muscle relaxant action through attenuating voltage-gated sodium channels in the brain stem.

Preparation Note

Tolperisone hydrochloride dissolves in water at a concentration that is greater than 20 mg/ml.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• Gefahrencodes: H302 + H312 + H332
• Sicherheitshinweise: P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): dust mask type N95 (US), Eyeshields, Gloves